Results 161 to 170 of about 2,572 (182)

Volumetric real-time multispectral optoacoustic tomography of biomarkers

Nature Protocols, 2011
Multispectral optoacoustic tomography (MSOT) has recently been developed to enable visualization of optical contrast and tissue biomarkers, with resolution and speed representative of ultrasound. In the implementation described here, MSOT enables operation in real-time mode by capturing single cross-sectional images in
Daniel Razansky, Andreas Buehler, Vasilis Ntziachristos   +2 more
openaire   +2 more sources

Developing a simulator for multispectral optoacoustic tomography

13th IEEE International Conference on BioInformatics and BioEngineering, 2013
The aim of this study was the development of a simulator for Multispectral Optoacoustic Tomography (MSOT). The modelling pathway of the simulator was separated into the optical, the acoustic and the reconstruction part in generating finally a photoacoustic image.
Efthymios Maneas, Stratis Tzoumas, Vasilis Ntziachristos, George Spyrou   +3 more
openaire   +1 more source

Continuous acquisition scanner for whole-body multispectral optoacoustic tomography

SPIE Proceedings, 2010
An essential problem dealing with three-dimensional optoacoustic imaging is the long data acquisition times associated with recording signals from multiple spatial projections, where signal averaging for each projection is applied to obtain satisfying signal-to-noise-ratio. This approach complicates acquisition and makes imaging challenging for most
Ma, R., Ntziachristos, V., Razansky, D.
openaire   +2 more sources

Multispectral optoacoustic tomography by means of normalized spectral ratio

Optics Letters, 2011
Quantification of biomarkers using multispectral optoacoustic tomography can be challenging due to photon fluence variations with depth and spatially heterogeneous tissue optical properties. Herein we introduce a spectral ratio approach that accounts for photon fluence variations.
Thomas Jetzfellner, Amir Rosenthal, Andreas Buehler, Karl-Hans Englmeier, Daniel Razansky, Vasilis Ntziachristos   +5 more
openaire   +2 more sources

Multispectral Optoacoustic Tomography (MSOT) Characterization in Resolving Molecular Biomarkers

2009
Fluorochromes are essential biological reporters in many areas of biomedical research and, in particular, molecular imaging applications. We demonstrate the basic performance characteristics of multispectral optoacoustic tomography in resolving fluorochromes in tissue-mimicking phantoms.
Taruttis, A., Deliolanis, N., Rosenthal, A., Razansky, D., Ntziachristos, V.   +4 more
openaire   +2 more sources

Sensitivity of molecular target detection by multispectral optoacoustic tomography (MSOT)

Medical Physics, 2009
Optoacoustic imaging is emerging as a noninvasive imaging modality that can resolve optical contrast through several millimeters to centimeters of tissue with the resolution achieved by ultrasound imaging. More recently, applied at multiple illumination wavelengths, multispectral optoacoustic tomography (MSOT) offered the ability to effectively ...
Daniel, Razansky, John, Baeten, Vasilis, Ntziachristos   +2 more
openaire   +2 more sources

siRNA liposome-gold nanorod vectors for multispectral optoacoustic tomography theranostics

Nanoscale, 2014
This study describes the simultaneous in vivo optoacousic imaging and siRNA-mediated gene silencing capabilities of a model theranostic vector system between liposomes and gold nanorods.
Taruttis, Adrian, Lozano, Neus, Nunes, Antonio, Jasim, Dhifaf, Beziere, Nicolas, Herzog, Eva, Kostarelos, Kostas, Ntziachristos, Vasilis   +7 more
openaire   +3 more sources

Spectral unmixing using component analysis in multispectral optoacoustic tomography

Molecular Imaging III, 2011
Multispectral optoacoustic (photoacoustic) tomography (MSOT) exploits high resolutions given by ultrasound detection technology combined with deeply penetrating laser illumination in the near infrared. Traces of molecules with different spectral absorption profiles, such as blood (oxy- and de-oxygenated) and biomarkers can be recovered using multiple ...
Stefan Morscher, Jürgen Glatz, Nikolaos C. Deliolanis, Andreas Buehler, Athanasios Sarantopoulos, Daniel Razansky, Vasilis Ntziachristos   +6 more
openaire   +1 more source

Optical Imaging Redefined: Advances in Multispectral Optoacoustic Tomography (MSOT)

Biomedical Optics 2014, 2014
The talk describes current progress with methods and applications for multispectral opto-acoustic imaging & outlines how new optoacoustic and fluorescence imaging concepts are necessary for accurate & quantitative molecular investigations in tissues.
openaire   +1 more source

Multispectral Optoacoustic Tomography—Volumetric Color Hearing in Real Time

IEEE Journal of Selected Topics in Quantum Electronics, 2012
Biomedical optoacoustics has emerged in the recent decade as a powerful tool for high-resolution visualization of optical contrast, overcoming a variety of longstanding limitations imposed by light scattering in deep tissues. But true performance of optoacoustic imaging techniques can only be exploited when excitation at multiple wavelengths is used in
openaire   +1 more source