Results 111 to 120 of about 1,068,731 (282)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Atualização das Figuras da subjetividade revolucionária: Proletariado versus Multidão
Revista de Políticas Públicas, 2014 The article examines the notion of revolutionary subjectivity in different authors and in different historical situations. Locates the postmodernity to the discussion around the idea that Marxism and negrism depart from certain theoretical heritage of ...
Flávio Bezerra de Farias +1 more
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Revolution in 1672? On the Philosophy of a Disproportion in History
Práticas da HistóriaIn the seventeenth century, the Dutch Republic was at the forefront of modernity, though not quite modern yet. The disproportion concerned a crisis that would burst out in 1672: a crisis of the bourgeoisie, the protagonist of modernity.
Thomas van Binsbergen
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
, 2011 [ES] Definición del término Multitud en el diccionario Dicter. [EN] Definition of the word Multitud in the dictionary Dicter.
openaire +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Entre precariedade e resistência: a cidade como espaço de produção e luta no capitalismo cognitivo
Ciências Sociais Unisinos, 2017 This article proposes to identify the relations between the changes in labor and the recent global cycle of struggles. The shared understanding in the investigation is that from the 1970s, capitalism goes through a transformation characterized for the ...
Carolina Salomão Corrêa
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