Results 201 to 210 of about 9,030 (299)

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

Advanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu, Xuting Zheng, Huinan Tong, Ying Liu, Xiaoxi Fan, Miao Xu, Ziyan Zhang, Li Zhang, Mingyan Liu, Ting Du, Heran Li, Guojun Liu   +11 more
wiley   +1 more source

A phase separation hypothesis for the biological function of PrP: the role of multivalent interactions at the plasma membrane. [PDF]

Biochem Soc Trans
Freire MH, Linden R, Cordeiro Y.
europepmc   +1 more source

Phosphonium Ionic Liquids for Electrochemical Energy Storage: Structure–Property–Interphase Relationships and Design Rule

Advanced Science, EarlyView.
Phosphonium ionic liquids offer a versatile platform for safer and more durable energy storage. This Review connects cation–anion structure with solvation, ion transport, electrochemical stability, and interphase formation across diverse battery chemistries.
Amir Haghipour, Ishanka Thennakoon, Aishwaryaba Jadeja, Daniel Rauber, Markus Gallei, Rolf Hempelmann, Sangwon Kim, Jungtae Kim   +7 more
wiley   +1 more source

Multivalency Enables Signal Processing at Single Protein Level. [PDF]

J Am Chem Soc
Wu X, Jia Y, Zhang T, Xiong Z, Ye Z, Yu G, Lei Y, Mao Z, Qu V, Dang B, Xu Z, Chen Z.   +11 more
europepmc   +1 more source

An Infusible Decellularized Extracellular Matrix Material Binds to Vasculature in Infarcted Myocardium and Induces Pro‐Reparative Gene Expression Following Acute Myocardial Infarction Through Inherent Avidity and Bioactive Signaling

Advanced Science, EarlyView.
To better characterize an infusible extracellular matrix (iECM) material, we applied size‐based fractionation to separate out components into two major fractions. We characterized these fractions to understand how material properties such as composition, morphology, and biochemical properties affect bioactive effects in the context of acute myocardial ...
Michael B. Nguyen, Alexander Chen, Quincy Lyons, Van K. Ninh, Maxwell C. McCabe, Colin Luo, Benjamin D. Bridgelal, Connor Uhre, Julian Cheng, Kate E. Reimold, Selena Cao, Kirk C. Hansen, Kevin R. King, Karen L. Christman   +13 more
wiley   +1 more source

Enhancing small-molecule-mediated translational control through multivalent RNA aptamers. [PDF]

Nucleic Acids Res
Feng HY, Wu XJ, Li XH, Liu Y, Xu L, Xing X.   +5 more
europepmc   +1 more source

CircFAM65A/CANX Condensates Sequester FAM134B to Inhibit ER‐phagy and Suppress Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
The novel circRNA circFAM65A suppresses HCC progression. Mechanistically, circFAM65A drives CANX phase separation, which recruits FAM134B into condensates and blocks its interaction with LC3, thereby inhibiting ER‐phagy and HCC progression. Importantly, targeted circFAM65A delivery represents a potential therapeutic strategy for HCC.
Wenxiu Ru, Lunbiao Gan, Yu Lu, Yujing Guo, Qian Huang, Sha Yin, Fengze Nie, Sijia Di, Jiaqi Ning, Siyu Yao, Huanhuan Wan, Le Liu, Zehua Liu, Fa Yang, Weijun Qin, Weihong Wen   +15 more
wiley   +1 more source

Symmetry-Guided Optical Control of Dynamic 1D Protein Self-Assembly and Precise In Vitro Initiation of Biomolecular Condensation. [PDF]

Small
Bae J, Jung Y.
europepmc   +1 more source

Intelligent Polymer Electrolytes for Next‐Generation Zinc‐Based Energy Storage Devices

Advanced Science, EarlyView.
Intelligent polymer electrolytes are organized into a three‐level hierarchy that advances zinc‐based energy storage from passive ion conduction toward active, adaptive, and intelligent operation. Molecular regulation of Zn+ coordination, water activity, desolvation, ion flux, and interfaces underpins adaptive self‐healing, anti‐freezing, adhesion, and ...
Sanath Kumar, Jhansirani Kesavan, Muhammad Asim, Atul Verma, Yen‐Pei Fu   +4 more
wiley   +1 more source

Hierarchy of Hydrophobic and Electrostatic Interactions in DNA-Membrane Phase Selectivity. [PDF]

ACS Appl Mater Interfaces
Wong SH, Lou Y, Chen Y, Morzy D, Bastings MMC.   +4 more
europepmc   +1 more source