Results 81 to 90 of about 9,030 (299)
Selective Enrichment of Hypermethylated DNA by a Multivalent Binding Platform
Advanced Materials Interfaces, 2022 The preselection of hypermethylated DNA (hmDNA) from liquid biopsy samples is key to enable early‐stage cancer diagnostics. Due to limited selectivity of the existing preselection approaches, however, wide integration in the clinic is currently ...
Ruben W. Kolkman +2 more
doaj +1 more source
Digitally Printed Eco‐Friendly Electronic Devices
Advanced Functional Materials, EarlyView.Fabrication of electronics using eco‐friendly materials through digital printing routes is a promising strategy for improving life cycle sustainability and reducing the environmental impacts of conventional manufacturing. This review highlights state‐of‐the‐art eco‐friendly materials, green ink formulations, various resource‐efficient digital printing ...
Nitheesh M. Nair +5 more
wiley +1 more source
Multivalent Carbonic Anhydrases Inhibitors [PDF]
International Journal of Molecular Sciences, 2019 Biomolecular recognition using a multivalent strategy has been successfully applied, this last decade on several biological targets, especially carbohydrate-processing enzymes, proteases, and phosphorylases. This strategy is based on the fact that multivalent interactions of several inhibitory binding units grafted on a presentation platform may ...
Carta, Fabrizio +3 more
openaire +3 more sources
, 2016 Multivalency iodine (I7+/I-) doped TiO2 were prepared via a combination of deposition−precipitation process and hydrothermal treatment. The as-prepared samples were characterized by X-ray diffraction, transmission electron microscopy, Brunauer−Emmett ...
Ling Wu (151826) +6 more
core +1 more source
Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics
Advanced Functional Materials, EarlyView.Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley +1 more source
Multivalent Ligands for Siglecs [PDF]
, 2010 Siglecs have emerged as an important family of immunomodulatory glycan-binding proteins that can bind sialoside ligands both on the same cell surface, in cis, and on other cells, in trans. Expression of siglecs varies among a variety of immune cells, and tools to probe siglecs on these cells are crucial to understanding their function.
Mary K, O'Reilly, James C, Paulson
openaire +2 more sources
Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine
Advanced Healthcare Materials, EarlyView.Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang +7 more
wiley +1 more source
Dimeric and Multimeric DNA Aptamers for Highly Effective Protein Recognition
Molecules, 2020 Multivalent interactions frequently occur in biological systems and typically provide higher binding affinity and selectivity in target recognition than when only monovalent interactions are operative.
Claudia Riccardi +3 more
doaj +1 more source
Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution
Advanced Healthcare Materials, EarlyView.Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk +6 more
wiley +1 more source
Carbohydrate inhibitors of cholera toxin
Beilstein Journal of Organic Chemistry, 2018 Cholera is a diarrheal disease caused by a protein toxin released by Vibrio cholera in the host’s intestine. The toxin enters intestinal epithelial cells after binding to specific carbohydrates on the cell surface.
Vajinder Kumar, W. Bruce Turnbull
doaj +1 more source