Results 51 to 60 of about 1,716,762 (293)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Multimodal neural correlates of childhood psychopathology

open access: yeseLife
Complex structural and functional changes occurring in typical and atypical development necessitate multidimensional approaches to better understand the risk of developing psychopathology.
Jessica Royer   +9 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Applied Multivariate Research, v.13 no.1 (complete version)

open access: yes, 2009
The first issue of Applied Multivariate Research edited by Dennis L. JacksonDigitized and published in SOAR:Shocker Open Access Repository by Wichita State University Libraries Technical Services.Multivariate models for three dimensional data / James W ...

core   +1 more source

Insights into a Renowned Fishery: Distinct Spatial Patterns, Environmental Predictors and Species Associations of Trophy-Class Spotted Seatrout (Cynoscion nebulosus [Cuvier 1830])

open access: yesFishes
Spotted Seatrout Cynoscion nebulosus (hereafter, trout) are one of the most heavily targeted sportfish along the Gulf coast. With recent regulation changes intended to reduce the harvest mortality of trout and promote a healthy trophy-class trout fishery
Catherine Eckert   +2 more
doaj   +1 more source

Multivariate and Multiscale Data Assimilation in Terrestrial Systems: A Review

open access: yesSensors, 2012
More and more terrestrial observational networks are being established to monitor climatic, hydrological and land-use changes in different regions of the World.
Harry Vereecken   +4 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Missing Data in Regression Models for Non-Commensurate Multiple Outcomes

open access: yesRevstat Statistical Journal, 2011
Biomedical research often involves the measurement of multiple outcomes in different scales (continuous, binary and ordinal). A common approach for the analysis of such data is to ignore the potential correlation among the outcomes and model each ...
Armando Teixeira-Pinto   +1 more
doaj   +1 more source

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