Results 241 to 250 of about 25,511,154 (361)

A Novel Multivariate Analysis: Overturning Long-Held Beliefs About Non-Photochemical Quenching. [PDF]

Physiol Plant
Ramakers LAI, Harbinson J, van Amerongen H.   +2 more
europepmc   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Multivariate Boosting for Integrative Analysis of High-Dimensional Cancer Genomic Data

Cancer Informatics, 2015
Lie Xiong, Pei-Fen Kuan, Jianan Tian, Sunduz Keles, Sijian Wang   +4 more
doaj  

Multivariate analysis of pomological and morphological diversity in Withania coagulans, a neglected medicinal plant. [PDF]

Sci Rep
Khadivi A, Mirheidari F, Tunç Y, Saeidifar A, Moradi Y.   +4 more
europepmc   +1 more source

Measuring the impact of principals' competence and facilities on teachers' achievement in Public Vocational High Schools in Palembang City: A multivariate analysis

Yuniarti Yuniarti, Jumadi Walajro
openalex   +2 more sources

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Univariate and multivariate analysis of the styrofoam fixation device on patient setup errors in radiotherapy. [PDF]

J Appl Clin Med Phys
Chen J, Guo Y, Wang C, Lin S, Shao L, Lan L, Guo F.   +6 more
europepmc   +1 more source

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

Advanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang, Wanxiang Niu, Yuanfei Wang, Peng Chen, Maolin Mu, Xiaoming Zhang, Ben Xu, Shanshan Hu, Chaoshi Niu, Pengfei Wu   +9 more
wiley   +1 more source

Perioperative Outcomes Associated with Intraoperative Hypothermia in Pediatric Patients with Preserved Functional Capacity Undergoing Anesthesia: A Multivariate Analysis. [PDF]

J Clin Med
Saezhang W, Oofuvong M, Kovitwanawong N, Yongyukantorn K.   +3 more
europepmc   +1 more source

A methodological proposal for a social and multivariate analysis in peri-urban areas during the ‘golden age’ of suburbanisation in Andalusia (Spain)1

J. Muñoz
openalex   +1 more source