Results 21 to 30 of about 988,211 (198)
COSIMA data analysis using multivariate techniques [PDF]
Geoscientific Instrumentation, Methods and Data Systems, 2015 We describe how to use multivariate analysis of complex TOF-SIMS (time-of-flight secondary ion mass spectrometry) spectra by introducing the method of random projections.
J. Silén +6 more
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EntropyThis study investigates the impact of data distribution and bootstrap resampling on the anomaly detection performance of the Isolation Forest (iForest) algorithm in statistical process control. Although iForest has received attention for its multivariate
Hyunyul Choi, Kihyo Jung
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Design of multivariate early warning management system for fully-mechanized coal mining equipment
Gong-kuang zidonghua, 2018 In view of problems of low accuracy, low efficiency and poor timeliness in current management mode of fully-mechanized coal mining equipment, a multivariate early warning management system for fully-mechanized coal mining equipment was designed.
YANG Rui, CAO Kai, WANG Jiyu
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Using a Multivariate Virtual Experiment for Uncertainty Evaluation with Unknown Variance
MetrologyVirtual experiments are a digital representation of a real measurement and play a crucial role in modern measurement sciences and metrology. Beyond their common usage as a modeling and validation tool, a virtual experiment may also be employed to perform
Manuel Marschall +5 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source