Results 141 to 150 of about 52,951 (307)

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

A radically different method of moments

open access: yesEURASIP Journal on Advances in Signal Processing
The four primary moment-based probability density estimation and associated moment-based parameter estimation methods used in classical statistical inference when the probability density functions for the observed data are unknown or are intractable are ...
William A. Gardner
doaj   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li   +13 more
wiley   +1 more source

Estimation of a Multivariate Density [PDF]

open access: yes, 1964
1 online resource (PDF, 22 pages)Cacoullos, Theophilos. (1964). Estimation of a Multivariate Density.
Cacoullos, Theophilos
core  

Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates

open access: yesAdvanced Science, EarlyView.
Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao   +4 more
wiley   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

open access: yesAdvanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang   +10 more
wiley   +1 more source

Calculation of Multivariate Normal Probabilities by Simulation, with Applications to Maximum Simulated Likelihood Estimation [PDF]

open access: yes
We discuss methods for calculating multivariate normal probabilities by simulation and two new Stata programs for this purpose: mvdraws for deriving draws from the standard uniform density using either Halton or pseudo-random sequences, and an egen ...
Lorenzo Cappellari, Stephen P. Jenkins
core  

High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency

open access: yesAdvanced Science, EarlyView.
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan   +11 more
wiley   +1 more source

Evaluating Density Forecasts [PDF]

open access: yes
We propose methods for evaluating density forecasts. We focus primarily on methods that are applicable regardless of the particular user's loss function.
Francis X. Diebold   +2 more
core  

Asymmetric multivariate normal mixture GARCH [PDF]

open access: yes, 2008
An asymmetric multivariate generalization of the recently proposed class of normal mixture GARCH models is developed. Issues of parametrization and estimation are discussed.
Mittnik, Stefan   +2 more
core  

Home - About - Disclaimer - Privacy