Results 191 to 200 of about 223,465 (247)

Sequential Change Detection with Local Differential Privacy. [PDF]

Entropy (Basel)
Zhang L, Liu X, Zhang R, Xie L.
europepmc   +1 more source

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

Advanced Science, EarlyView.
OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu, Wen Zheng, Chao Yang, Tao Yang, Qiuyu Chen, Ping Lu, Huan Yang, Jun Liu, Bin Yang   +8 more
wiley   +1 more source

Impact of RAASIs on Potassium and Mortality in a Large Cohort of Hemodialysis Patients: Practical Excursus and Comparison Between Traditional Statistics and Machine Learning. [PDF]

J Clin Med
Calabrese V, Stancanelli MR, Sberna ME, Taverna G, Geraci G, Cernaro V, Santoro D.   +6 more
europepmc   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

Advanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao, Li Peng, Xiaobin Zheng, Cong Tan, Chuang Wang, Qijiang Xiong, Weiming Chen, Zhao Yang   +7 more
wiley   +1 more source

Multivariate hematological and biochemical profiling reveals conserved physiological modules in Brahman- and Charolais-crossbred beef cattle under tropical smallholder systems. [PDF]

Vet World
Tana S, Thongseela J, Sripalwit P, Raksaseri P, Sangwijit K, Panase P, Intawicha P, Saengwong S.   +7 more
europepmc   +1 more source

Transformer‐Based PET/CT Fusion Enables Preoperative Prediction and Prognostic Stratification of Spread Through Air Spaces in Lung Adenocarcinoma

Advanced Science, EarlyView.
An eight‐stream 2.5D Transformer integrates complementary PET metabolic and CT morphologic information to estimate spread‐through‐air‐spaces risk before surgery in lung adenocarcinoma. The model generalizes across independent centers, while its continuous risk score independently stratifies progression‐free survival, supporting further prospective ...
Xin‐Yu Zhu, Meng Meng, Zhen‐Zhen Wang, Deng‐Lu Lu, Ya‐Min Wei, Xu‐Chang Mi, Xing‐Yu Mu, Wei Fu   +7 more
wiley   +1 more source

Genomic structure, introgression, niche overlap and morphological variation challenge species delimitation in Thymus sect. Mastichina. [PDF]

Ann Bot
Nieto-Lugilde D, Del Valle JC, Martín-Carretié EM, Doblas-Pruvost D, Williams-Marland B, Ortiz MÁ, Jiménez-López FJ, López-Tirado J, García-Cárdenas FJ, Berjano R.   +9 more
europepmc   +1 more source

A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis

Advanced Science, EarlyView.
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang, Miaoyu Li, Tiantian Li, Xiaojie Zang, Haiyang Shi, Yaru Liu, Chengcheng Zhang, Jianxin Zhao, Qixiao Zhai, Wei Chen, Fengwei Tian   +10 more
wiley   +1 more source

Hypotheses on physiopathogenic mechanisms of fecal incontinence in Wolfram syndrome. [PDF]

IBRO Neurosci Rep
Orssaud C.
europepmc   +1 more source

On the sampling distributions of classical statistics in multivariate analysis

Osaka Mathematical Journal, 1953
openaire   +4 more sources