The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells
Purely geometric 3D Voronoi models predict the organisation of epithelial shells. The interplay of curvature, geometry, and topology enriches the number of pentagons in shells with lower number of cells. Small MDCK cysts and Mouse embryos match the top polygonal configurations in a compactness‐based ranking derived from the Voronoi model. In conclusion,
Laura Morato +9 more
wiley +1 more source
Genetic Susceptibility to Diabetic Retinopathy in the Thrace Region: Role of IL-18 (-607 C/A, -137 G/C) and IL-8 (-251 A/T) Variations. [PDF]
Ay A, Alkanli N, Tabakoglu NT, Guclu H.
europepmc +1 more source
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu +10 more
wiley +1 more source
Concentration, Information, and Distributional Stability in High-Dimensional Portfolios: A Talagrand Stability Index Approach. [PDF]
Georgescu I, Kinnunen J.
europepmc +1 more source
Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha +13 more
wiley +1 more source
Bayesian Estimation of Marginal Quantiles with Missing Data in a Multivariate Regression Framework. [PDF]
Morán-Vásquez RA +2 more
europepmc +1 more source
MXene‐Based Room‐Temperature NO2 Gas Sensors: A Meta‐Analysis
This study presents the first comprehensive meta‐analysis of MXene‐based NO2 sensors, decoding 32 study characteristics across 61 peer‐reviewed studies. By isolating materials chemistry as the primary performance driver over device‐level parameters, the authors establish a methodological blueprint and a predictive structure–function map to accelerate ...
Alexander Khort +3 more
wiley +1 more source
Evaluating Missing Data Imputation Strategies for Environmental Mixture Models: A Simulation Study and Applied Analysis. [PDF]
Boafo YS, Mostafa S, Obeng-Gyasi E.
europepmc +1 more source
This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao +8 more
wiley +1 more source
Alterations in the Multivariate Organization of Plasma Fatty Acid Profiles and Spontaneous Behavior in an AlCl<sub>3</sub>-Induced Rat Model of Neurotoxicity. [PDF]
Alzweiri M +6 more
europepmc +1 more source

