Results 101 to 110 of about 93,507 (297)

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Korovkin-type convergence results for multivariate Shepard formulae

Journal of Numerical Analysis and Approximation Theory, 2009
We present a new convergence proof for classic multivariate Shepard formulae within the context of Korovkin-type convergence results for positive operators on spaces of continuous real valued functions.
Oliver Nowak
doaj   +2 more sources

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Multivariate error function based neural network approximations

Journal of Numerical Analysis and Approximation Theory, 2014
Here we present multivariate quantitative approximations of real and complex valued continuous multivariate functions on a box or \(\mathbb{R}^{N},\) \(N\in \mathbb{N}\), by the multivariate quasi-interpolation, Baskakov type and quadrature type neural ...
George A. Anastassiou
doaj   +2 more sources

Proceedings of the Workshop on Kernel Functions and Meshless Methods honoring the 65th birthday of Robert Schaback, held in Göttingen (Germany), 14−15 January 2011 [PDF]

Dolomites Research Notes on Approximation, 2011
ContentGerlind Plonka-HochPreface • page 2Martin D. BuhmannApproximation in Göttingen: some remarks on Robert Schaback's work on its theory and applications • pages 3−14Len Bos • Stefano De Marchi • Alvise Sommariva • Marco VianelloOn multivariate ...
Martin Buhmann, Stefano De Marchi, Gerlind Plonka-Hoch   +2 more
doaj  

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Finite difference grid generation by multivariate blending function interpolation [PDF]

The General Interpolants Method (GIM) code which solves the multidimensional Navier-Stokes equations for arbitrary geometric domains is described. The geometry module in the GIM code generates two and three dimensional grids over specified flow regimes ...
Anderson, P. G., Spradley, L. W.
core   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

EUPollMap: the European atlas of contemporary pollen distribution maps derived from an integrated Kriging interpolation approach [PDF]

Earth System Science Data
Modern and fossil pollen data are widely used in paleoenvironmental research to characterize past environmental changes in a given location. However, their discrete and discontinuous nature can limit the inferences that can be made from them.
F. Oriani, F. Oriani, G. Mariethoz, M. Chevalier, M. Chevalier   +4 more
doaj   +1 more source