Results 151 to 160 of about 958,747 (333)
Minimizing batch‐to‐batch variability of a live virus vaccine by process analytical technologies
Abstract For bioprocesses producing live virus, such as enterovirus Coxsackievirus A21, viral titer (infectivity basis) decay rates can exceed 30% within a day. Consequently, harvest timing is paramount. To optimize titer at harvest, a continuous viral product titer model was generated to elucidate kinetics.
Katherine Forrester+4 more
wiley +1 more source
Multivariate Hermite interpolation by algebraic polynomials: A survey
Rudolph A. Lorentz
openalex +1 more source
Impact of bioreactor process parameters and yeast biomass on Raman spectra
Abstract In‐line Raman spectroscopy combined with chemometric modeling is a valuable process analytical technology (PAT) providing real‐time quantitative information on cell culture compounds. Considering that compound quantification through chemometric models depends on pre‐processing to maintain consistent changes in intensity at certain wavenumbers,
Maarten Klaverdijk+3 more
wiley +1 more source
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang+6 more
wiley +1 more source
Abstract Background The ASTRUM‐005 study previously demonstrated a significant overall survival (OS) benefit with serplulimab (a programmed death 1 inhibitor) plus chemotherapy versus chemotherapy alone in previously untreated extensive‐stage small‐cell lung cancer (ES‐SCLC).
Ying Cheng+32 more
wiley +1 more source
Deterministic sparse interpolation of black-box multivariate polynomials using Kronecker type substitutions [PDF]
Gao Xiao‐Shan, Huang Qiaolong
openalex +1 more source
Abstract Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of aggressive non‐Hodgkin's lymphoma with distinct clinical and molecular heterogeneity. DLBCL that arises in extranodal organs is particularly linked to poor prognosis. This study aimed to determine the clinical and molecular characteristics of extranodal involvement (
Si‐Yuan Chen+46 more
wiley +1 more source
Expected term bases for generic multivariate Hermite interpolation
Marcin Dumnicki
openalex +2 more sources