Results 41 to 50 of about 30,181 (227)

An unusual presentation of pediatric acute lymphoblastic leukemia with parotid gland involvement and dactylitis

open access: yesTurkish Journal of Hematology, 2010
Mumps infection during the course of childhood acute lymphoblastic leukemia (ALL) treatment has been reported to have a mild course and this was related to the intrinsic low cytopathological effect of the virus, contrasting with the severe course of ...
Şule Ünal   +8 more
doaj   +3 more sources

Inhibitors of the interferon response enhance virus replication in vitro.

open access: yes, 2014
This work was supported by the University of St Andrews (CSA, CES) and the Wellcome Trust (grant 087751/A/08/Z) (RER).Virus replication efficiency is influenced by two conflicting factors, kinetics of the cellular interferon (IFN) response and induction ...
Richard E. Randall   +8 more
core   +1 more source

Molecular characterization of mumps viruses from the 2022–2023 outbreak reveals circulation of multiple genotypes in Uganda

open access: yesVirology Journal
Mumps is a highly contagious viral disease caused by the mumps virus (MuV), a member of the genus Orthorubulavirus in the family Paramyxoviridae. Although effective vaccines exist, mumps vaccination is not yet part of Uganda’s routine immunization ...
Phionah Tushabe   +12 more
doaj   +1 more source

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi   +6 more
wiley   +1 more source

Activation of the beta interferon promoter by paramyxoviruses in the absence of virus protein synthesis

open access: yes, 2012
Conflicting reports exist regarding the requirement for virus replication in interferon (IFN) induction by paramyxoviruses. Our previous work has demonstrated that pathogen-associated molecular patterns capable of activating the IFN-induction cascade are
Killip, M. J.   +14 more
core   +1 more source

The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya [PDF]

open access: yes, 2009
Background Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in infants. The rate of decay of RSV-specific maternal antibodies (RSV-matAb), the factors affecting cord blood levels, and the relationship between ...
Nokes D. James   +26 more
core   +1 more source

Mumps Vaccines: Current Challenges and Future Prospects

open access: yesFrontiers in Microbiology, 2020
Five decades have passed since the first mumps vaccine was licensed. Over this period, a resurgence of mumps infections has been recorded worldwide. Although global mumps infections have been controlled through vaccination, outbreaks are still on the ...
Iman Almansour
doaj   +1 more source

How Health Systems ‘Software’ Factors Affect Frontline Health Workers' Humanitarian Response Efforts During Infectious Disease Outbreaks in the Rohingya Refugee Camps, Cox's Bazar, Bangladesh

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Humanitarian settings face a growing healthcare workforce crisis marked by staff shortages, unsafe working conditions, and limited professional development. Despite being critical intermediaries in outbreak responses, demands on health workers come at a substantial cost to their health and wellbeing.
Georgia Venner   +9 more
wiley   +1 more source

Validation of the diagnosis of autism in general practitioner records [PDF]

open access: yes, 2004
Background: We report on the validity of the computerized diagnoses of autism in a large case-control study investigating the possible association between autism and the measles, mumps and rubella vaccine in the UK using the General Practitioner Research
Eric Fombonne   +34 more
core   +1 more source

Sensibilite Comparee de Quatre Cultures Cellulaires Differentes Pour L'lsolement et L'Identification de Virus des OreiMons [PDF]

open access: yesActa Medica Iranica, 1978
Three differentes continous cell lines (Am 57. Hela • Vero) and primary cell culture of human embryo kidney"nare compared with regard to their .susceptibility for Isolation of mumps v i r u s from saliva and cerebrospinal fluid.
Fakhrossadat Mohammadzadeh Kiai
doaj  

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