SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng +18 more
wiley +1 more source
Laser peripheral iridotomy for treating recurrent uveitis-glaucoma-hyphema plus syndrome with a scleral fixed intraocular lens: a case report. [PDF]
Yang F +6 more
europepmc +1 more source
Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen +3 more
wiley +1 more source
Assessing the impact of co-created community initiatives on health and equity: a protocol for population-based surveys within the CAIR project in Elche, Spain. [PDF]
Moreno-Llamas A +8 more
europepmc +1 more source
Different from the current research trends that mainly focus on optimizing a single color system, a universal organic–inorganic hybrid strategy is proposed, aiming to synergistically enhance the luminescent properties of red, green, and blue multi‐color inorganic long‐persistent phosphorescent materials by trap depth modulation and antenna effect of ...
Ting Tan +7 more
wiley +1 more source
Fumarate hydratase-deficient renal cell carcinoma: A case report and review of literature
Mingyu Ma +3 more
doaj +1 more source
Vulnerability assessment to tropical cyclones in the North Caribbean Coast of Nicaragua (1988-2022). [PDF]
Muñoz-Requene L +2 more
europepmc +1 more source
Tailored D‐π Conjugation Boosts Piezocatalytic CO2 Reduction in a Platinum(II)‐Acetylide Framework
The highly conjugated metalII‐acetylide framework demonstrates efficient ultrasound‐driven conversion of CO2 to CO. The piezoelectric field generated by ultrasound facilitates electron transfer from the tetraphenylene π‐column to the MII‐bis(acetylide) moiety, enabling CO2 activation. Compared to PdII‐ and NiII‐based analogues, the stronger d–π orbital
Mude Zhu +6 more
wiley +1 more source
Choroidal changes correlate with type 1 neovascular activity in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy. [PDF]
Huang X +7 more
europepmc +1 more source
A foldable bimodal sensor integrates a triboelectric nanogenerator and graphene piezoresistive effect into a monolithic laser‐induced graphene film. It enables synchronous non‐contact and tactile perception, achieving a distance of 110 mm, a sensitivity of 11.2 kPa−1, and a response time of 10 ms.
Weixiong Yang +10 more
wiley +1 more source

