Results 211 to 220 of about 129,150 (264)

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang   +8 more
wiley   +1 more source

GEP-based ecological functional zoning and land use drivers in coastal southeast China. [PDF]

open access: yesiScience
Liu X   +11 more
europepmc   +1 more source

Comparative Analysis of Psychosocial Risks and Leadership in Municipal Government Agencies: A Study Based on NOM-035-STPS-2018 in Zacatecas, Mexico. [PDF]

open access: yesInt J Environ Res Public Health
Villagrán Rueda S   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy