Results 221 to 230 of about 1,251,769 (293)

PLOD1 Catalytic Activity Stabilizes ENO1 by Limiting FBXW7‐dependent Degradation to Promote Glycolysis and TMZ Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
PLOD1 interacts with ENO1 and limits its FBXW7‐dependent ubiquitination and proteasomal degradation through a mechanism requiring PLOD1 catalytic activity. ENO1 stabilization sustains glycolysis, promoting glioblastoma cell proliferation, migration, and temozolomide resistance.
Fen Xue   +4 more
wiley   +1 more source

In-sewer microplastics drive microbial metabolic shifts toward enhanced methanogenesis. [PDF]

open access: yesEnviron Sci Ecotechnol
Wang Y   +7 more
europepmc   +1 more source

Scalable Fabrication of MOF Glass Membranes for Gas Separation via Stepwise Phase Transition

open access: yesAdvanced Science, EarlyView.
Metal‐organic framework (MOF) glass membranes, with their excellent processability and permanent pore structure, have great potential for gas separation applications. However, during large‐scale fabrication, defects and obvious cracks are prone to occur due to the limitations of powder processing.
Mao Ye   +14 more
wiley   +1 more source

Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD

open access: yesAdvanced Science, EarlyView.
This study establishes a novel cisplatin‐induced rat model of PAH/PVOD and identifies a conserved mechanistic axis—FANCL impairment, DNA damage accumulation, and endothelial dysfunction—triggered by cisplatin or mitomycin C across pulmonary arteries, veins, and microvessels.
Shiyun Liu   +20 more
wiley   +1 more source

Protonation Modification of Commercial OPBI as Binders Toward High‐Performance High‐Temperature PEM Fuel Cells

open access: yesAdvanced Science, EarlyView.
Commercial OPBI binders is regulated via a facile formic‐acid protonation strategy without disrupting the polymer backbone. Protonation introduces positively charged benzimidazole sites, inducing interchain electrostatic repulsion that loosens chain packing, enlarges intermolecular spacing, and promotes uniform binder dispersion over catalyst surfaces.
Jinzhen Huang   +5 more
wiley   +1 more source

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