Results 41 to 50 of about 794,813 (311)

The effect of the integration of health services on health care usage among patients with type 2 diabetes in North Karelia, Finland

BMC Health Services Research, 2021
Background The need to improve the care of people with complex care requirements has been driving the reforms integrating care processes. This study examines the effect of the integration of health services on health care usage and the processes and ...
Katja Wikström, Marja-Leena Lamidi, Päivi Rautiainen, Hilkka Tirkkonen, Petri Kivinen, Tiina Laatikainen   +5 more
doaj   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Features of municipal services digitalization in Iraq

Наука Красноярья
Background. The digitalization of municipal services represents a critically important direction for modernizing public administration in developing countries.
Svetlana V. Panikarova, Saif S. M. AL-zuwaini   +1 more
doaj   +1 more source

Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials

Advanced Science, EarlyView.
Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan, Hengheng Zhao, Haotian Wang, Zhanjie Liu, Qian Li, Weifeng Zhang, Qingsong Zhao, Liqun Zhang, Jun Liu   +8 more
wiley   +1 more source

Rozvoj infrastruktury komunálního podnikání v kontextu externího zajišťování komunálních služeb (Development of Infrastructure of the Municipal Enterpreneurship in the Context of the Outsourced Providing for Municipal Services) [PDF]

DETUROPE, 2014
The aim of the paper is to discuss the situation of the municipal enterpreneurship in some EU member countries (namely Great Britain, France, Germany, Austria and Scandinavian countries) with regards to the process of privatization running out since ...
Karel Lacina, Hana Matoušková
doaj  

Cottage Cheese or Chicken? An AFSCME Fight for Public Food Service [PDF]

, 1990
[Excerpt] Confronted with mounting fiscal problems, many state and local government officials consider privatization or contracting out of public services a quick fix for their difficulties.
Magid, Marcia
core   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

The Quality of Selected Municipal Services During the COVID-19 Pandemic in the Opinion of Students of Cracow Universities

Economics and Environment, 2020
The paper aims to present the results of studies of students' opinions on the quality of municipal services available in Krakow and its changes during the Covid-19 pandemic.
Jakub Bartak, Dariusz Firszt, Marek Jabłoński, Łukasz Jabłoński   +3 more
doaj   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

Advanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu, Xue Leng, Jiang Long, Zhengao Liao, Xiaoqin An, Xuezheng Ai, Dan Long, Changqing Li, Bo Huang, Yue Zhou, Shiwu Dong, Chencheng Feng   +11 more
wiley   +1 more source

DEVELOPMENT OF SYSTEM OF THE MULTIPURPOSE CENTERS OF PROVIDING THE STATE AND MUNICIPAL SERVICES TO THE POPULATION (ON THE EXAMPLE OF PRIMORSKY KRAI)

RUDN Journal of Public Administration, 2016
The article deals with improving the quality of the provision and accessibility of public and municipal services. With the rapid development of telecommunications technology procedures for obtaining services and information to signifi cantly expand and ...
Eugeniya O Zapoleva, Anna A Zakharchenko, Victor V Pit, Elena S Mudrik   +3 more
doaj