Results 261 to 270 of about 872,668 (343)
Adaptation of global One Health evaluation framework to municipal levels in Fukuoka, Japan. [PDF]
Yokota F +8 more
europepmc +1 more source
Logic‐Gated HSV‐TK/GCV Suicide Gene Circuit for Triple‐Negative Breast Cancer
The BRAS comprises two modular genetic components driven by distinct tumor‐specific promoters and a failsafe layer with the NOT gate. This multi‐input logic gate circuit enables precise, specific expression of HSV‐TK in breast cancer cells with hardly expression in normal cell and effectively inhibits tumor growth in a triple‐negative breast cancer ...
Shasha Tang +10 more
wiley +1 more source
Quality and safety for Sámi users of health and care services: a cross-sectional study from Norway. [PDF]
Olsen RM +3 more
europepmc +1 more source
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu +7 more
wiley +1 more source
Japan Energy Database with hourly and municipal-scale estimates to support local energy system analysis. [PDF]
Ono R +5 more
europepmc +1 more source
This study presents a novel “in vivo–in vitro” therapeutic strategy for spinal cord injury by leveraging magnetically responsive piezoelectric nanomaterials. These nanomaterials enable targeted delivery of localized electrical stimulation at the injury site through noninvasive external magnetic actuation, thereby promoting axonal regeneration and ...
Zhihang Xiao +9 more
wiley +1 more source
Zooming In: Assessing the Transferability of SDMs From Large to Small Spatial Extents. [PDF]
Seuren JRG +3 more
europepmc +1 more source
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong +13 more
wiley +1 more source
Municipal deprivation and cardiometabolic outcomes in Mexican adults: findings from ENSANUT 2021-2023. [PDF]
Contreras-Loya D +4 more
europepmc +1 more source

