Results 111 to 120 of about 366,908 (315)

Information in connection with the Municipality of Stellenbosch vol. 1, no. 34, 1962-08-24

open access: yes, 1962
ims_1962-08-24.pdf derived from archival TIFF file. Digital copies were created from the original hard copy collection of the newsletter held by Stellenbosch Library and Information Service Africana Collection.IMS (Information in connection with the ...
Liebenberg, S. W. J.
core  

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

Information in connection with the Municipality of Stellenbosch vol. 1, no. 10, 1960-04-29

open access: yes, 1960
ims_1960-04-29.pdf derived from archival TIFF file. Digital copies were created from the original hard copy collection of the newsletter held by Stellenbosch Library and Information Service Africana Collection.IMS (Information in connection with the ...
Dempsey, W. C.
core  

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

Information in connection with the Municipality of Stellenbosch vol. 1, no. 44, 1963-08-23

open access: yes, 1963
ims_1963-08-23.pdf derived from archival TIFF file. Digital copies were created from the original hard copy collection of the newsletter held by Stellenbosch Library and Information Service Africana Collection.IMS (Information in connection with the ...
Dempsey, W. C.
core  

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Splicing of fibronectin gene contribute to the aneurysmal dilatation of arteriovenous fistula

open access: yesRenal Failure
Patients with end-stage renal disease often require arteriovenous fistula (AVF) creation for hemodialysis. However, nearly 40% of patients develop aneurysmal dilatation of AVF (AVFA) after surgery, which can lead to prolonged bleeding at puncture sites ...
Hai Wang   +10 more
doaj   +1 more source

Information in connection with the Municipality of Stellenbosch vol. 1, no. 25, 1961-09-29

open access: yes, 1961
ims_1961-09-29.pdf derived from archival TIFF file. Digital copies were created from the original hard copy collection of the newsletter held by Stellenbosch Library and Information Service Africana Collection.IMS (Information in connection with the ...
Liebenberg, S. W. J.
core  

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

Project HELLO, SENIORS

open access: yesBaltic Journal of Sport and Health Sciences
Since 2023, the HELLO, SENIORS project has been taking place in the city of Kaunas, aimed at preventing falls and injuries. Residents of Kaunas aged 60 and over who participate in the project have the opportunity to take part in free and various ...
Laura Motužytė, Gerda Kuzmarskienė
doaj   +1 more source

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