Results 251 to 260 of about 366,908 (315)

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Association between same-sex partnership certificate schemes and mental health in sexual and gender minority adults: nationwide cross-sectional study in Japan. [PDF]

BMJ Open
Tatsuno Y, Minami T, Tomio J, Tabuchi T, Miyawaki A.   +4 more
europepmc   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

An updated herpetological inventory of the Agusan Marsh Wildlife Sanctuary, eastern Mindanao Island, Philippines. [PDF]

Zookeys
Sanguila MB, Labaja ACO, Bernstein JM, Brown RM.   +3 more
europepmc   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

COVID-19 Mortality and Temporal Trends in a Mid-Sized Southern Brazilian City (2020-2023): A Population-Based Retrospective Study. [PDF]

Health Sci Rep
De Sá CA, Lutinski JA, Rodrigues-Junior SA, Zuge SS, Barretta JC, Corbellini F, Bones UA, Ventura-Silva J, Corralo VDS.   +8 more
europepmc   +1 more source

Zn(C2H4NO2)2(SO2CH3NH2)2 and Zn(C2H4NO2)2[SO2(NH2)2]: Regulation of Unique ZnO(C2H4NO2)2 Units by Polar Tetrahedrons for Balanced UV Nonlinear Optical Performance

Advanced Science, EarlyView.
The modulation of polar tetrahedra enabled the synthesis of an outstanding short‐wave UV NLO crystal, Zn(C2H4NO2)2[SO2(NH2)2], which achieves a rare balance of a large bandgap (5.93 eV), high birefringence (Δn = 0.126 at 546 nm), and strong SHG response (1.36 × KDP), especially achieving excellent phase‐matching throughout the full transparency range ...
Chenjie Cui, Yuchen Yan, Xin Wen, Jindong Chen, Jiyang Wang, Zhanggui Hu, Ning Ye, Guang Peng   +7 more
wiley   +1 more source

Prevalence and factors associated with dual contraceptive use among young women in Ntungamo municipality, southwestern Uganda: a community-based cross-sectional study. [PDF]

Reprod Health
Namara B, Baine SO, Ninsiima HI, Mugarura R.   +3 more
europepmc   +1 more source

Mechanically Adaptive Polyimide Interfaces for Stable High‐Voltage NCM–Sulfide All‐Solid‐State Batteries

Advanced Science, EarlyView.
A mechanically adaptive polyimide interface dynamically stabilizes single‐crystal cathodes in sulfide all‐solid‐state batteries. By integrating robust chemical coordination with viscoelastic compliance, this smart coating suppresses parasitic reactions and accommodates cyclic volume expansion.
Jiatao Wu, Wenjin Li, Rui Wang, Peng Wang, Kaiyuan Deng, Chengshuai Chang, Chuan Xie, Lei Yao, Guangliang Gary Liu   +8 more
wiley   +1 more source

Review of the families Mycteridae, Pythidae and Salpingidae (Coleoptera, Tenebrionoidea) of Bulgaria. [PDF]

Biodivers Data J
Gradinarov D, Petrova Y, Sivilov O.
europepmc   +1 more source