Results 151 to 160 of about 250,477 (263)
PINCH proteins orchestrate vascular mural cell homeostasis through integrated signaling and transcriptional networks. [PDF]
Wang C +10 more
europepmc +1 more source
CADASIL is the major cause of early‐onset stroke and cognitive dysfunction, including dementia. It is caused by mutations in the NOTCH3 receptor that result in the formation of protein aggregates in the small vessel walls of the brain. We demonstrated that NOTCH3 CADASIL variant receptor aggregation is strictly dependent on interactions with NOTCH3 ...
Haijiang Wang +9 more
wiley +1 more source
Automated image inpainting for historical artifact restoration using hybridisation of transfer learning with deep generative models. [PDF]
Swathi B, Rao DBJ.
europepmc +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Ring-like (Donut-Shaped) Intracranial Aneurysms: A Warning Morphology of Mural Jet Flow and Pre-Rupture Instability. [PDF]
Nestorović D +5 more
europepmc +1 more source
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng +7 more
wiley +1 more source
UNH Child Study Center Celebrates New Mural Sept. 24: Richard Haynes Created Looking In, Looking Out In Collaboration With Preschoolers [PDF]
Nimmo, John, Potier, Beth
core +1 more source
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside +11 more
wiley +1 more source
Ureteric stromal progenitors give rise to kidney inner cortical pericytes via an arterial mural cell intermediate. [PDF]
Luo PM, Ahuja NH, Carroll TJ, Cleaver O.
europepmc +1 more source

