Results 191 to 200 of about 79,529 (297)

Addenbrooke's Art and Murals [PDF]

open access: yesJournal of the Royal Society of Medicine, 1996
openaire   +2 more sources

Prospective Diagnostic Accuracy of Focused Frontal‐Branch Ultrasonography in Giant Cell Arteritis

open access: yesACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Objective To evaluate the diagnostic accuracy, reproducibility, and acquisition time of focused bilateral frontal‐branch ultrasonography based on intima‐media thickness (IMT) in suspected giant cell arteritis (GCA). Methods In this prospective single‐center study, 171 patients underwent color Doppler ultrasonography of the temporal and large arteries ...
Giuseppe Germanò   +6 more
wiley   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen   +8 more
wiley   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

open access: yesBiological Reviews, Volume 101, Issue 5, Page 2265-2278, October 2026.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido   +2 more
wiley   +1 more source

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