Results 41 to 50 of about 51,246 (254)

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Narrativas visuales de los tapietes: arte mural en una comunidad indígena del norte argentino

Revista del CISEN, 2019
En este artículo exploro de qué manera un proyecto cuyo objetivo fue el mejoramiento de las viviendas y de la comunidad generó la pintura de murales en los cuales emergió una heterogeneidad de representaciones visuales que apelan a la identidad, la ...
Silvia María Hirsch
doaj  

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

La Asimilación Mexicana: Colombia en los años treinta – El caso de Ignacio Gómez Jaramillo

Historia y Memoria, 2013
Durante la década de los treinta, artistas como Ignacio Gómez Jaramillo tomaron el muralismo mexicano como una parte importante de sus carreras y así mismo doptaron la iniciativa de realizar por primera vez en Colombia arte público.
Juanita Solano Roa
doaj   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

Mujeres y disidencias en los murales de Alberdi. Fútbol, barrio y feminismo

Avatares de la Comunicación y la Cultura
En el presente trabajo nos propusimos realizar una aproximación analítica, en cuanto lectura situada, contemporánea, provisoria y empírica, de los murales de Barrio Alberdi que retratan a mujeres y disidencias vinculadas al Club Atlético Belgrano ...
Débora Majul, María Emilia Cejas
doaj   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

Shaping identities through Street Art. Iconography of social claims in Orgosolo's Murales

Disegnare con, 2020
Nowadays, street art is one of the most common public art manifestations in bigger cities. However, there are case studies that show how this form of visual communication has a long history and can strengthen the capacity of the self-assertion also of ...
Michele Valentino, Enrico Cicalò
doaj  

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, EarlyView.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

Emilio B. Coutaret. Artista y agente cultural multifacético

Revista del Museo de La Plata
En este trabajo se estudian las obras que el artista francés Emilio Bonnet Coutaret (1863-1949) realizó para el Museo de La Plata en 1922. Se inicia con un breve recorrido por su trayectoria artística, docente y en gestión cultural, para luego avanzar ...
Marcela Andruchow
doaj   +1 more source