Results 41 to 50 of about 13,690 (279)

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi   +8 more
wiley   +1 more source

TMCrack-Net: A U-Shaped Network with a Feature Pyramid and Transformer for Mural Crack Segmentation

open access: yesApplied Sciences, 2022
The detection of crack information is very important in mural conservation. In practice, the number of ancient murals is scarce, and the difficulty of collecting digital information about murals leads to minimal data being collected.
Meng Wu, Min Jia, Jia Wang
doaj   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

Rereading the Themes and Imagery of Birds in the Qajar Wall Paintings of Mazandaran with a Literary and Mystical Approach [PDF]

open access: yesهنرهای زیبا. هنرهای تجسمی
Due to the creativity of her artists in using decorations, Iran’s architecture is full of beauty, variation, and aesthetic. Bird motifs in historical native buildings, both independently and in combination with other forms, go far beyond the aesthetic ...
Marjaneh Naderi Gorzoddini   +1 more
doaj   +1 more source

CREATE Resilience Through Science, Art, and Community Engagement

open access: yesCommunity Science, 2023
Resilience, specifically community resilience, has a range of definitions but several core elements, including social cohesion and collaboration. Importantly, community‐driven goals and approaches tend to be more effective.
Kathryn A. Semmens   +3 more
doaj   +1 more source

Primary mural endocarditis [PDF]

open access: yesEuropean Heart Journal, 2007
A 57-year-old male was admitted with a 2-week history of fever, rigours, and confusion and a single episode of retrosternal chest pain. He had recently undergone a circumcision. Clinical examination revealed a temperature of 38.3°C and a balanitis. Urinanalysis revealed haematuria and proteinuria.
Peadar F, McKeown   +2 more
openaire   +2 more sources

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

open access: yesAdvanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che   +9 more
wiley   +1 more source

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao   +15 more
wiley   +1 more source

Building social resilience through visual instruments in Polish public space in the era of Russia's aggression against Ukraine

open access: yesDefence Science Review, 2022
Objectives The purpose of the article was an attempt to answer the question of the impact of murals created in Polish public space on building social resilience in the era of war in Ukraine.
Katarzyna Dojwa-Turczyńska
doaj   +1 more source

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