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Identification and Characterization of Cell Wall Proteins of a Toxic Dinoflagellate Alexandrium catenella Using 2‐D DIGE and MALDI TOF‐TOF Mass Spectrometry [PDF]

Evidence-Based Complementary and Alternative Medicine, Volume 2011, Issue 1, 2011., 2011
The cell wall is an important subcellular component of dinoflagellate cells with regard to various aspects of cell surface‐associated ecophysiology, but the full range of cell wall proteins (CWPs) and their functions remain to be elucidated. This study identified and characterized CWPs of a toxic dinoflagellate, Alexandrium catenella, using a ...
Da-Zhi Wang, Hong-Po Dong, Cheng Li, Zhang-Xian Xie, Lin Lin, Hua-Sheng Hong   +5 more
wiley   +8 more sources

Insights into acylation mechanisms: co‐expression of serine carboxypeptidase‐like acyltransferases and their non‐catalytic companion paralogs

The Plant Journal, 2022
SUMMARY Serine carboxypeptidase‐like acyltransferases (SCPL‐ATs) play a vital role in the diversification of plant metabolites. Galloylated flavan‐3‐ols highly accumulate in tea (Camellia sinensis), grape (Vitis vinifera), and persimmon (Diospyros kaki).
Shengbo Yao, Yajun Liu, Juhua Zhuang, Yue Zhao, Xinlong Dai, Changjuan Jiang, Zhihui Wang, Xiaolan Jiang, Shuxiang Zhang, Yumei Qian, Yuling Tai, Yunsheng Wang, Haiyan Wang, D. Xie, Liping Gao, Tao Xia   +15 more
semanticscholar   +1 more source

Carboxypeptidase A3—A Key Component of the Protease Phenotype of Mast Cells

Cells, 2022
Carboxypeptidase A3 (CPA3) is a specific mast cell (MC) protease with variable expression. This protease is one of the preformed components of the secretome.
D. Atiakshin, Andrey M. Kostin, I. Trotsenko, V. Samoilova, I. Buchwalow, M. Tiemann   +5 more
semanticscholar   +1 more source

Genome-wide analysis of the serine carboxypeptidase-like protein family in Triticum aestivum reveals TaSCPL184-6D is involved in abiotic stress response

BMC Genomics, 2021
The serine carboxypeptidase-like protein (SCPL) family plays a vital role in stress response, growth, development and pathogen defense. However, the identification and functional analysis of SCPL gene family members have not yet been performed in wheat ...
Xiaomin Xu, Lili Zhang, Wan Zhao, Liang Fu, Yuxuan Han, Keke Wang, Lu-Yu Yan, Ye Li, Xiaohong Zhang, Dong-hong Min   +9 more
semanticscholar   +1 more source

High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity

bioRxiv, 2020
A novel coronavirus (SARS-CoV-2) has emerged to a global pandemic and caused significant damages to public health. Human angiotensin-converting enzyme 2(ACE2) was identified as the entry receptor for SARS-CoV-2.
Jinghua Lu, P. Sun
semanticscholar   +1 more source

Insights into the l,d-Transpeptidases and d,d-Carboxypeptidase of Mycobacterium abscessus: Ceftaroline, Imipenem, and Novel Diazabicyclooctane Inhibitors

Antimicrobial Agents and Chemotherapy, 2020
Mycobacterium abscessus is a highly drug-resistant nontuberculous mycobacterium (NTM). Efforts to discover new treatments for M. abscessus infections are accelerating, with a focus on cell wall synthesis proteins (M. abscessus l,d-transpeptidases 1 to 5 [
Khalid M. Dousa, Sebastian G. Kurz, M. Taracila, T. Bonfield, C. Bethel, M. D. Barnes, S. Selvaraju, Ayman M. Abdelhamed, Barry N. Kreiswirth, W. Boom, S. Kasperbauer, Charles L Daley, R. Bonomo   +12 more
semanticscholar   +1 more source

Carboxypeptidase B2 and carboxypeptidase N in the crosstalk between coagulation, thrombosis, inflammation, and innate immunity

Journal of Thrombosis and Haemostasis, 2018
Two basic carboxypeptidases, carboxypeptidase B2 (CPB2) and carboxypeptidase N (CPN) are present in plasma. CPN is constitutively active, whereas CPB2 circulates as a precursor, procarboxypeptidase B2 (proCPB2), that needs to be activated by the thrombin–
Lawrence L.K. Leung, John Morser
semanticscholar   +1 more source

Dissecting carboxypeptidase E: properties, functions and pathophysiological roles in disease

Endocrine Connections, 2017
Since discovery in 1982, carboxypeptidase E (CPE) has been shown to be involved in the biosynthesis of a wide range of neuropeptides and peptide hormones in endocrine tissues, and in the nervous system. This protein is produced from pro-CPE and exists in
Lin Ji, Huan-Tong Wu, Xiaoyan Qin, Rongfeng Lan   +3 more
semanticscholar   +1 more source

MicroRNA-146a promote cell migration and invasion in human colorectal cancer via carboxypeptidase M/src-FAK pathway

OncoTarget, 2017
Colorectal cancer (CRC) is one of the most common cancers worldwide, and microRNAs play important roles in CRC progression. This study aimed to investigate the roles of miR-146a-5p in human CRC and their molecular mechanisms.
Di Lu, Qunyan Yao, C. Zhan, Zhang Le-meng, Hong-chun Liu, Yu Cai, Chuantao Tu, Xi Li, Y. Zou, Shuncai Zhang   +9 more
semanticscholar   +1 more source

Role of Cytosolic Carboxypeptidase 5 in Neuronal Survival and Spermatogenesis

Scientific Reports, 2017
Proteins may undergo a type of posttranslational modification – polyglutamylation, where a glutamate residue is enzymatically linked to the γ-carboxyl group of a glutamate in the primary sequence of proteins and additional glutamates are then ...
Hui-Yuan Wu, P. Wei, J. Morgan
semanticscholar   +1 more source