Results 91 to 100 of about 358,693 (195)

Improvement of Electrochemical Conditions for Detecting Redox Reaction of K3[Fe(CN)6] toward the Application in Norovirus Aptasensor

open access: yesElectrochemistry, 2020
Electrochemical biosensors have attracted significant attention as a novel tool for the sensitive detection of pathogens and contaminants, with the potential capability of rapid, on-site diagnosis. In this study, we intended to improve the sensitivity of
Seiya HIRANO   +6 more
doaj   +1 more source

Bacteria-mediated stabilization of murine norovirus

open access: yesbioRxiv, 2022
Enteric viruses encounter various bacteria in the host which can impact infection outcomes. The interactions between noroviruses and enteric bacteria are not well understood.
Melissa R. Budicini, Julie K. Pfeiffer
semanticscholar   +1 more source

Murine norovirus infection in Brazilian animal facilities

open access: yesExperimental Animals, 2017
Murine norovirus (MNV) is a single-stranded positive-sense RNA virus of the Caliciviridae family. MNV has been reported to infect laboratory mice with the ability to cause lethal infections in strains lacking components of the innate immune response.
Marcus A.F. Corat   +4 more
openaire   +4 more sources

Characterization of Intestinal Dendritic Cells in Murine Norovirus Infection [PDF]

open access: yesThe Open Immunology Journal, 2011
We have shown that respiratory viral infections drive allergic disease through dendritic cells, whether gastrointestinal viruses induce allergies is not known. Norovirus infections are a major cause of gastroenteritis in humans. We used murine norovirus (MNV) to explore the effect of MNV infection on gastrointestinal conventional DCs (cDCs) and ...
Desire Hunter   +6 more
openaire   +2 more sources

Commensal Viruses Promote Intestinal Stem Cell Regeneration Following Radiation Damage by Inhibiting Hyperactivation of RIG‐I and Notch Signals

open access: yesAdvanced Science, EarlyView.
Ionizing radiation disrupts gut virome and bacteriome. Gut commensal viruses protect against intestinal damage and promote stem cell regeneration by inhibiting hyperactivation of RIG‐I and Notch signaling in stem cells. Fecal virome transplantation (FVT) from healthy donors can serve as a potential therapeutic intervention by enriching phages targeting
Xiaotong Zhao   +17 more
wiley   +1 more source

Evaluation of murine norovirus as a surrogate for human norovirus and hepatitis A virus in heat inactivation studies [PDF]

open access: yesJournal of Applied Microbiology, 2009
To determine the suitability of murine norovirus (MNV) as a surrogate for human norovirus (HuNoV) in heat inactivation studies.MNV, hepatitis A virus (HAV) and HuNoV genogroup I and II (GI and GII) specific real-time quantitative reverse transcription (qRT)-PCR assays were used to determine the effects of heat exposure (63 and 72 degrees C) for up to ...
Malet Rivera-Aban   +2 more
openaire   +3 more sources

Assessing the Efficacy of Small Molecule Inhibitors in a Mouse Model of Persistent Norovirus Infection

open access: yesBio-Protocol, 2018
Human norovirus is the most common cause of acute gastroenteritis worldwide, resulting in estimated mortality of ~210,000 each year, of whom most are children under the age of five. However, norovirus can infect people of all age groups.
Jana Van Dycke   +2 more
doaj   +1 more source

A gut microbiota‐bile acid axis inhibits the infection of an emerging coronavirus by targeting its cellular receptor aminopeptidase N

open access: yesiMeta, EarlyView.
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang   +12 more
wiley   +1 more source

Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch   +1 more
wiley   +1 more source

Exploring the impact of a chemical disinfectant and an antiviral drug for RNA virus management in the Mediterranean fruit fly mass‐rearing

open access: yesInsect Science, EarlyView.
Abstract The Mediterranean fruit fly is an agricultural pest of a wide variety of fruit crops. An effective method to counteract them in the field is through the application of the sterile insect technique, which requires the mass‐production of sterile males.
Luis Hernández‐Pelegrín   +5 more
wiley   +1 more source

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