Results 121 to 130 of about 358,693 (195)
Recent advances in understanding noroviruses [version 1; referees: 2 approved]
Noroviruses are the leading cause of acute gastroenteritis around the world. An individual living in the United States is estimated to develop norovirus infection five times in his or her lifetime. Despite this, there is currently no antiviral or vaccine
Eric Bartnicki+3 more
doaj +1 more source
Antiviral Activity of Carbon Dots: Strategies and Mechanisms of Action
Carbon dots are capable to interact with viruses through different mechanisms of action, having an antiviral and virucidal effect: inhibition of viral entry into the cells, disruption of viral replication, and damage of the virion structure. The COVID‐19 pandemic profoundly changes the perception of the impact of viral diseases on society and the ...
Plinio Innocenzi+2 more
wiley +1 more source
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus+3 more
wiley +1 more source
Establishment of a Novel Caco‐2‐Based Cell Culture System for Human Sapovirus Propagation
We identified that both Caco‐2 cells and in‐house Caco‐2/Cas9 cells are susceptible to human sapovirus (HuSaV) infection. By performing two rounds of single‐cell cloning from Caco‐2/Cas9 cells, we successfully established a highly susceptible cell line, designated as Caco‐2MC.
Yuya Fukuda+7 more
wiley +1 more source
Virucidal efficacy of glutaraldehyde for instrument disinfection
Aim: Glutaraldehyde (GDA) is an active ingredient in many instrument disinfectants and is effective against a broad spectrum of microorganisms. In the past, the virus-inactivating properties of these products were mainly claimed based on quantitative ...
Brill, Florian H.H.+7 more
doaj +1 more source
Innate Immunity Never “NODs” Off: NLRs Regulate the Host Anti‐Viral Immune Response
ABSTRACT A robust innate immune response is essential in combating viral pathogens. However, it is equally critical to quell overzealous immune signaling to limit collateral damage and enable inflammation resolution. Pattern recognition receptors are critical regulators of these processes.
Mackenzie K. Woolls+5 more
wiley +1 more source
Feline calicivirus (FCV) is frequently used as a surrogate of human norovirus. We investigated eligibility of FCV for anti-viral assay by investigating the stability of infectivity and pH sensitivity in comparison with other viruses. We found that infectivities of FCV and murine norovirus (MNV) are relatively unstable in infected cells compared with ...
Kosuke Oda+9 more
openaire +4 more sources
Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
Here the authors show that a murine norovirus causes self-resolving diarrhea in the absence of systemic disease in wild-type neonatal mice and show that lymphocytes affect disease in a dual manner.
Alexa N. Roth+9 more
doaj +1 more source
Edible films can be designed to serve as carriers of antimicrobial agents and be used to control pathogenic foodborne viruses and bacteria. This research tested this concept by dissolving green tea extract (GTE) in chitosan film-forming solutions (FFS ...
Collins Amankwaah+3 more
semanticscholar +1 more source
The final optimized mucoadhesive film had good tensile strength, swelling capacity, compatibility with oral mucosa, and flexibility. It also demonstrated desirable stability and adhesion ability. Regarding bioactivity, the film was found to have desirable antioxidant capacity, and it was non‐toxic to fibroblast cells when diluted to certain ...
Kubra Goktas+4 more
wiley +1 more source