Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-γ-mediated inhibition of norovirus replication in macrophages [PDF]
, 2012 Noroviruses (NVs) cause the majority of cases of epidemic nonbacterial gastroenteritis worldwide and contribute to endemic enteric disease. However, the molecular mechanisms responsible for immune control of their replication are not completely ...
Duan, Erning +7 more
core +2 more sources
Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
Nature Communications, 2020 Here the authors show that a murine norovirus causes self-resolving diarrhea in the absence of systemic disease in wild-type neonatal mice and show that lymphocytes affect disease in a dual manner.
Alexa N. Roth +9 more
doaj +1 more source
Journal of Food Protection, 2010 We evaluated and optimized each step in an analytical method for detecting norovirus from various foods. We characterized the buffers needed for eluting norovirus from foods such as ham and lettuce. Two different concentration methods, polyethylene glycol (PEG) precipitation and hollow fiber ultrafiltration (HUF), were compared using both murine ...
Kim Minjung, Hyeonjin Park, GwangPyo Ko
openaire +3 more sources
, 2009 In November 2004, 116 individuals in an elderly nursing home in El Grao de Castellón, Spain were symptomatically infected with genogroup II.4 (GII.4) norovirus. The global attack rate was 54.2%. Genotyping of 34 symptomatic individuals regarding the FUT2
Abu Mallouh, Reem +12 more
core +1 more source
Human norovirus transmission due to contaminated fresh fruit and vegetables [PDF]
, 2012 Almost any ready-to-eat fruit or vegetable that has been contaminated with pathogens, either from the environment, human or animal feces or through storage, processing and handling, could potentially cause disease.
Radin Dragoslava
core +2 more sources
Evaluation of Four Antiseptics Using a Novel Murine Norovirus
Experimental Animals, 2012 We isolated a novel murine norovirus (MNV), MT30-2 strain, from feces of conventional mice in Japan to evaluate the virucidal activity of four antiseptics. The MNV MT30-2 strain was inactivated by as little as 0.2% (w/v) povidone-iodine (PVP-I) and 0.1% (w/v) sodium hypochlorite (NaOCl) treatment as determined by a novel plaque assay.
Kazunori Maebashi +6 more
openaire +4 more sources
Protective and Aggravating Effects of Nlrp3 Inflammasome Activation in IBD Models: Influence of Genetic and Environmental Factors [PDF]
, 2012 Background: Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation due to dysregulation of the mucosal immune system.
Bauer, Christian +4 more
core +1 more source
Glycolysis Is an Intrinsic Factor for Optimal Replication of a Norovirus
mBio, 2019 The metabolic pathways of central carbon metabolism, glycolysis and oxidative phosphorylation (OXPHOS), are important host factors that determine the outcome of viral infections and can be manipulated by some viruses to favor infection.
Karla D. Passalacqua +8 more
doaj +1 more source
Sapovirus translation requires an interaction between VPg and the cap binding protein eIF4E. [PDF]
, 2014 UNLABELLED: Sapoviruses of the Caliciviridae family of small RNA viruses are emerging pathogens that cause gastroenteritis in humans and animals. Molecular studies on human sapovirus have been hampered due to the lack of a cell culture system.
Chaudhry, Yasmin +4 more
core +2 more sources
The Impact of Capsid Proteins on Virus Removal and Inactivation During Water Treatment Processes [PDF]
, 2015 This study examined the effect of the amino acid composition of protein capsids on virus inactivation using ultraviolet (UV) irradiation and titanium dioxide photocatalysis, and physical removal via enhanced coagulation using ferric chloride.
Abbaszadegan, Morteza A. +3 more
core +3 more sources