Results 11 to 20 of about 13,538 (226)

Experimental Adaptation of Murine Norovirus to Calcium Hydroxide. [PDF]

Front Microbiol, 2022
Slaked lime (calcium hydroxide) is a commonly used disinfectant for fecal sludge. Although viruses are inactivated by lime treatment, whether RNA viruses adapt to lime treatment has not yet been determined. Here, we show that murine norovirus developed higher tolerance during serial passages with lime treatment.
Oishi W, Sato M, Kubota K, Ishiyama R, Takai-Todaka R, Haga K, Katayama K, Sano D.   +7 more
europepmc   +6 more sources

Effects of Essential Oils and Hydrolates on the Infectivity of Murine Norovirus. [PDF]

Viruses, 2023
The use of natural substances with antiviral properties might reduce foodborne viral diseases. In this study, we evaluated the virucidal effect of Citrus limon and Thymus serpyllum essential oils (EOs) and of Citrus Limon, Thymus serpyllum and Thymus vulgaris hydrolates on murine norovirus (MNV), a human norovirus surrogate.
Cozzi L, Vicenza T, Battistini R, Masotti C, Suffredini E, Di Pasquale S, Fauconnier ML, Ercolini C, Serracca L.   +8 more
europepmc   +6 more sources

MDA-5 recognition of a murine norovirus. [PDF]

PLoS Pathogens, 2008
Noroviruses are important human pathogens responsible for most cases of viral epidemic gastroenteritis worldwide. Murine norovirus-1 (MNV-1) is one of several murine noroviruses isolated from research mouse facilities and has been used as a model of ...
Stephen A McCartney, Larissa B Thackray, Leonid Gitlin, Susan Gilfillan, Herbert W Virgin, Marco Colonna   +5 more
doaj   +6 more sources

Murine Norovirus: a Model System To Study Norovirus Biology and Pathogenesis [PDF]

Journal of Virology, 2006
Human noroviruses are the major cause of nonbacterial, epidemic gastroenteritis worldwide ([19][1], [23][2], [33][3], [46][4]) and cause significant numbers of endemic cases, as well. One study from 1999 estimated that, in the United States alone, human noroviruses cause 23 million cases ...
Christiane E. Wobus, Larissa B. Thackray, Herbert W. Virgin   +2 more
openalex   +5 more sources

Functional Analysis of RNA Structures Present at the 3′ Extremity of the Murine Norovirus Genome: the Variable Polypyrimidine Tract Plays a Role in Viral Virulence [PDF]

, 2010
Interactions of host cell factors with RNA sequences and structures in the genomes of positive-strand RNA viruses play various roles in the life cycles of these viruses.
Dalan Bailey, Ioannis Karakasiliοtis, Surender Vashist, Liliane Chung, Jivan Reese, Nora McFadden, Alicia Benson, Felix Yarovinsky, Peter Simmonds, Ian Goodfellow   +9 more
core   +8 more sources

Plaque Assay for Murine Norovirus [PDF]

Journal of Visualized Experiments, 2012
Murine norovirus (MNV) is the only member of the Norovirus genus that efficiently grows in tissue culture. Cell lysis and cytopathic effect (CPE) are observed during MNV-1 infection of murine dendritic cells or macrophages. This property of MNV-1 can be used to quantify the number of infectious particles in a given sample by performing a plaque assay ...
Mariam B. Gonzalez-Hernandez, Juliana Bragazzi Cunha, Christiane E. Wobus   +2 more
openalex   +4 more sources

Structural Studies on the Shapeshifting Murine Norovirus. [PDF]

Viruses, 2021
Noroviruses are responsible for almost a fifth of all cases of gastroenteritis worldwide. The calicivirus capsid is composed of 180 copies of VP1 with a molecular weight of ~58 kDa. This coat protein is divided into the N-terminus (N), the shell (S) and C-terminal protruding (P) domains. The S domain forms a shell around the viral RNA genome, while the
Sherman MB, Williams AN, Smith HQ, Pettitt BM, Wobus CE, Smith TJ.   +5 more
europepmc   +6 more sources

Reverse Genetics Mediated Recovery of Infectious Murine Norovirus [PDF]

Journal of Visualized Experiments, 2012
Human noroviruses are responsible for most cases of human gastroenteritis (GE) worldwide and are recurrent problem in environments where close person-to-person contact cannot be avoided (1, 2). During the last few years an increase in the incidence of outbreaks in hospitals has been reported, causing significant disruptions to their operational ...
Armando Arias, Luis Ureña, Lucy Thorne, Muhammad Amir Yunus, Ian Goodfellow   +4 more
  +6 more sources

Antibody Is Critical for the Clearance of Murine Norovirus Infection [PDF]

Journal of Virology, 2008
ABSTRACT Human noroviruses cause more than 90% of epidemic nonbacterial gastroenteritis. However, the role of B cells and antibody in the immune response to noroviruses is unclear. Previous studies have demonstrated that human norovirus specific antibody levels increase upon infection, but they may not be protective against ...
K. A. Chachu, D. W. Strong, A. D. LoBue, C. E. Wobus, R. S. Baric, H. W. Virgin   +5 more
openalex   +5 more sources

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus. [PDF]

PLoS Pathog, 2020
Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major determinant of cell tropism, host range, and pathogenesis. The bona fide receptor for HNoV is unknown. Recently, we identified CD300lf as a proteinaceous receptor for MNoV.
Graziano VR, Walker FC, Kennedy EA, Wei J, Ettayebi K, Strine MS, Filler RB, Hassan E, Hsieh LL, Kim AS, Kolawole AO, Wobus CE, Lindesmith LC, Baric RS, Estes MK, Orchard RC, Baldridge MT, Wilen CB.   +17 more
europepmc   +9 more sources