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Comparison of ELISA attachment and infectivity assays for murine norovirus
Journal of Virological Methods, 2012Human noroviruses cause approximately 58% of foodborne illnesses in the USA. Recent studies have shown norovirus attachment to the carbohydrates moieties of host cellular receptors. Using murine norovirus (MNV) as a surrogate, an ELISA method was utilized to assess attachment through binding to host cell receptors; MNV attachment was correlated to ...
Kalmia E. Kniel, Kirsten A. Hirneisen
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Inactivation of Human and Murine Norovirus by High-Pressure Processing
Foodborne Pathogens and Disease, 2011The effect of high hydrostatic pressure (HPP) was evaluated for inactivation of murine norovirus (MNV), a propagable norovirus (NoV), and human NoV genogroup II.4. Inactivation of MNV was assessed by viral culturing (50% tissue culture infectious dose [TCID(50)]) and real-time reverse-transcription-polymerase chain reaction (RT-qPCR), whereas NoV ...
Dolores Rodrigo +3 more
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Differences in the viability of murine norovirus in different aquatic locations
Marine Pollution Bulletin, 2016Norovirus is detected from shellfish and environmental water more frequently in winter than in other seasons. However, there is no report regarding its viability in actual seawater in situ. We investigated the viability of murine norovirus strain 1 (MNV-1), a surrogate for human norovirus, in 2 types of aquatic locations, a seawater pool carrying ...
Bon Kimura +7 more
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Food and Environmental Virology, 2010
Human noroviral infections are generally more common during winters in temperate regions. This study used a murine norovirus (MNV) as a human norovirus surrogate to test the effect of water temperature (4 and 25°C) on virus survival and its susceptibility to the levels of monochloramine (~1.89 ppm) to terminally disinfect municipally treated potable ...
Regina Keller +4 more
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Human noroviral infections are generally more common during winters in temperate regions. This study used a murine norovirus (MNV) as a human norovirus surrogate to test the effect of water temperature (4 and 25°C) on virus survival and its susceptibility to the levels of monochloramine (~1.89 ppm) to terminally disinfect municipally treated potable ...
Regina Keller +4 more
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Identification of Viral Determinants of Murine Norovirus Pathogenesis
2012Human noroviruses are responsible for the majority of cases of epidemic non-bacterial gastroenteritis. Despite their importance as human pathogens, knowledge of the viral life cycle and host pathogenesis is limited due to the lack of practical models to study.
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Virucidal activity of different alcohols against murine norovirus, a surrogate of human norovirus
Journal of Hospital Infection, 2011Paulmann, Dajana +5 more
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