Trim7 does not have a role in the restriction of murine norovirus infection <i>in vivo</i>. [PDF]
Trim7 is an E3 ubiquitin ligase that was recently identified as a central regulator of host-viral interactions with both pro-viral and anti-viral activity in cell culture.
Annaswamy Srinivas M+6 more
europepmc +2 more sources
A Pilot Study of Aerosolization of Infectious Murine Norovirus in an Experimental Setup. [PDF]
Human norovirus is transmitted mainly via the faecal-oral route, but norovirus disease outbreaks have been reported in which airborne transmission has been suggested as the only explanation.
Purhonen R+5 more
europepmc +2 more sources
Single-cell transcriptional analysis of murine norovirus infection in a human intestinal cell line. [PDF]
Noroviruses are a major agent of acute gastroenteritis in humans, but host cell requirements for efficient replication in vitro have not been established.
Matsushima Y+11 more
europepmc +2 more sources
Interferons and tuft cell numbers are bottlenecks for persistent murine norovirus infection. [PDF]
Noroviruses (NoVs) are a leading cause of viral gastroenteritis. Despite global clinical relevance, our understanding of how host factors, such as antiviral cytokines interferons (IFNs), modulate NoV population dynamics is limited. Murine NoV (MNoV) is a
Aggarwal S+9 more
europepmc +2 more sources
Oxidative Stress Markers and Histopathological Changes in Selected Organs of Mice Infected with Murine Norovirus 1 (MNV-1). [PDF]
This paper describes the effects of murine norovirus (MNV) infection on oxidative stress and histopathological changes in mice. This study uses histopathological assays, enzymatic and non-enzymatic antioxidant markers, and total oxidative status and ...
Janicka P+8 more
europepmc +2 more sources
Antiviral Activities of Asarones and Rhizomes of Acorus gramineus on Murine Norovirus. [PDF]
Noroviruses (NVs) are a major cause of foodborne diseases worldwide. The rhizomes of Acorus gramineus (AGR) have been used as a traditional medicinal plant and a food additive.
Kim H+4 more
europepmc +2 more sources
Efficacy of washing produce in removing human coronavirus OC43 and murine norovirus. [PDF]
Fresh produce is often a vehicle for the transmission of foodborne pathogens such as human norovirus. Thus, it is recommended to wash the surface of produce before consumption, and one of the most common ways to wash produce is by rinsing under running ...
Dallner M, Harlow J, Nasheri N.
europepmc +2 more sources
MDA-5 recognition of a murine norovirus. [PDF]
Noroviruses are important human pathogens responsible for most cases of viral epidemic gastroenteritis worldwide. Murine norovirus-1 (MNV-1) is one of several murine noroviruses isolated from research mouse facilities and has been used as a model of ...
Stephen A McCartney+5 more
doaj +6 more sources
Preventing the Transmission of Murine Norovirus to Mice (Mus musculus) by Using Dry-heat Sterilization. [PDF]
A critical component of an animal care biosecurity plan includes the sterilization of materials that come into direct contact with the animals. Dry-heat sterilization is gaining popularity in animal research facilities due to lower cost, less space ...
Lee JC, Bidot WA, Nunamaker EA.
europepmc +2 more sources
Attach Me If You Can: Murine Norovirus Binds to Commensal Bacteria and Fungi [PDF]
The presence of commensal bacteria enhances both acute and persistent infection of murine noroviruses. For several enteric viral pathogens, mechanisms by which these bacteria enhance infection involve direct interactions between the virus and bacteria ...
Jasmine L. Madrigal+6 more
doaj +2 more sources