Results 31 to 40 of about 13,727 (226)
Aerosolization and recovery of viable murine norovirus in an experimental setup. [PDF]
Alsved M +5 more
europepmc +3 more sources
Norovirus is the leading cause of acute viral gastroenteritis. Both human and murine noroviruses attach to commensal bacteria belonging to the mammalian gut flora, and binding levels are influenced by nutrients present in bacterial media.
Kendall J. Long +2 more
doaj +1 more source
Plaque Assay for Murine Norovirus [PDF]
Murine norovirus (MNV) is the only member of the Norovirus genus that efficiently grows in tissue culture. Cell lysis and cytopathic effect (CPE) are observed during MNV-1 infection of murine dendritic cells or macrophages. This property of MNV-1 can be used to quantify the number of infectious particles in a given sample by performing a plaque assay ...
Gonzalez-Hernandez, Mariam B. +2 more
openaire +2 more sources
Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response. [PDF]
Ubiquitin (Ub) is a vital regulatory component in various cellular processes, including cellular responses to viral infection. As obligate intracellular pathogens, viruses have the capacity to manipulate the ubiquitin (Ub) cycle to their advantage by ...
Jeffrey W Perry +5 more
doaj +1 more source
Heat-Denatured Lysozyme Inactivates Murine Norovirus as a Surrogate Human Norovirus [PDF]
AbstractHuman norovirus infects humans through the consumption of contaminated food, contact with the excrement or vomit of an infected person and through airborne droplets that scatter the virus through the air. Being highly infectious and highly viable in the environment, inactivation of the norovirus requires a highly effective inactivating agent ...
Hajime Takahashi +8 more
openaire +2 more sources
Murine Norovirus: a Model System To Study Norovirus Biology and Pathogenesis [PDF]
Human noroviruses are the major cause of nonbacterial, epidemic gastroenteritis worldwide ([19][1], [23][2], [33][3], [46][4]) and cause significant numbers of endemic cases, as well. One study from 1999 estimated that, in the United States alone, human noroviruses cause 23 million cases ...
Christiane E, Wobus +2 more
openaire +2 more sources
Human noroviruses are the leading cause of foodborne gastroenteritis worldwide and disease outbreaks have been linked to contaminated surface waters as well as to produce consumption.
Shu Zhu +8 more
doaj +1 more source
Characterization of Ozone Disinfection of Murine Norovirus [PDF]
ABSTRACT Despite the importance of human noroviruses (NoVs) in public health, little information concerning the effectiveness of ozone against NoVs is available. We determined the efficacy of ozone disinfection using murine norovirus (MNV) as a surrogate of human NoV.
Mi Young, Lim +3 more
openaire +2 more sources
Pathology caused by persistent murine norovirus infection [PDF]
Subclinical infection of murine norovirus (MNV) was detected in a mixed breeding group of WT and Stat1 −/− mice with no outward evidence of morbidity or mortality. Investigations revealed the presence of an attenuated MNV variant that did not cause cytopathic effects in RAW264.7 cells or death in Stat1 −/− mice ...
Shortland, Amita +7 more
openaire +2 more sources
Reverse Genetics Mediated Recovery of Infectious Murine Norovirus [PDF]
Human noroviruses are responsible for most cases of human gastroenteritis (GE) worldwide and are recurrent problem in environments where close person-to-person contact cannot be avoided (1, 2). During the last few years an increase in the incidence of outbreaks in hospitals has been reported, causing significant disruptions to their operational ...
Arias, Armando +4 more
openaire +2 more sources

