Determination of murine norovirus aerosol concentration during toilet flushing. [PDF]
Murine norovirus (MNV) was used as a surrogate for human viral pathogens (e.g., norovirus) to determine if toilet flushing resulted in the aerosolization of virus.
Boles C, Brown G, Nonnenmann M.
europepmc +2 more sources
Analysis of Synchronous and Asynchronous In Vitro Infections with Homologous Murine Norovirus Strains Reveals Time-Dependent Viral Interference Effects [PDF]
Viral recombination is a key mechanism in the evolution and diversity of noroviruses. In vivo, synchronous single-cell coinfection by multiple viruses, the ultimate prerequisite to viral recombination, is likely to be a rare event and delayed secondary ...
Louisa F. Ludwig-Begall+7 more
doaj +2 more sources
Assignment of Ala, Ile, LeuproS, Met, and ValproS methyl groups of the protruding domain of murine norovirus capsid protein VP1 using methyl–methyl NOEs, site directed mutagenesis, and pseudocontact shifts [PDF]
The protruding domain (P-domain) of the murine norovirus (MNV) capsid protein VP1 is essential for infection. It mediates receptor binding and attachment of neutralizing antibodies.
Thorben Maaß+6 more
openalex +2 more sources
On the Use of Persian Gum for the Development of Antiviral Edible Coatings against Murine Norovirus of Interest in Blueberries. [PDF]
In the last decades, berries have been identified as important vehicles for the transmission of foodborne viruses and different strategies are being explored to eliminate or reduce viral contamination in these fruits.
Sharif N+5 more
europepmc +2 more sources
Murine Norovirus: a Model System To Study Norovirus Biology and Pathogenesis [PDF]
Human noroviruses are the major cause of nonbacterial, epidemic gastroenteritis worldwide ([19][1], [23][2], [33][3], [46][4]) and cause significant numbers of endemic cases, as well. One study from 1999 estimated that, in the United States alone, human noroviruses cause 23 million cases ...
Christiane E. Wobus+2 more
openalex +5 more sources
Membrane asymmetry facilitates murine norovirus entry and persistent enteric infection
Norovirus, the leading cause of gastroenteritis worldwide, is a non-enveloped virus whose tropism is determined in part by the expression patterns of entry receptors.
Brittany Stewart+3 more
openalex +2 more sources
Plaque Assay for Murine Norovirus [PDF]
Murine norovirus (MNV) is the only member of the Norovirus genus that efficiently grows in tissue culture. Cell lysis and cytopathic effect (CPE) are observed during MNV-1 infection of murine dendritic cells or macrophages. This property of MNV-1 can be used to quantify the number of infectious particles in a given sample by performing a plaque assay ...
Mariam B. Gonzalez-Hernandez+2 more
openalex +4 more sources
Structural Studies on the Shapeshifting Murine Norovirus. [PDF]
Noroviruses are responsible for almost a fifth of all cases of gastroenteritis worldwide. The calicivirus capsid is composed of 180 copies of VP1 with a molecular weight of ~58 kDa. This coat protein is divided into the N-terminus (N), the shell (S) and C-terminal protruding (P) domains. The S domain forms a shell around the viral RNA genome, while the
Sherman MB+5 more
europepmc +6 more sources
Reverse Genetics Mediated Recovery of Infectious Murine Norovirus [PDF]
Human noroviruses are responsible for most cases of human gastroenteritis (GE) worldwide and are recurrent problem in environments where close person-to-person contact cannot be avoided (1, 2). During the last few years an increase in the incidence of outbreaks in hospitals has been reported, causing significant disruptions to their operational ...
Armando Arias+4 more
+6 more sources
Antibody Is Critical for the Clearance of Murine Norovirus Infection [PDF]
ABSTRACT Human noroviruses cause more than 90% of epidemic nonbacterial gastroenteritis. However, the role of B cells and antibody in the immune response to noroviruses is unclear. Previous studies have demonstrated that human norovirus specific antibody levels increase upon infection, but they may not be protective against ...
K. A. Chachu+5 more
openalex +5 more sources