Results 41 to 50 of about 358,693 (195)

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus. [PDF]

PLoS Pathog, 2020
Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major determinant of cell tropism, host range, and pathogenesis. The bona fide receptor for HNoV is unknown. Recently, we identified CD300lf as a proteinaceous receptor for MNoV.
Graziano VR, Walker FC, Kennedy EA, Wei J, Ettayebi K, Strine MS, Filler RB, Hassan E, Hsieh LL, Kim AS, Kolawole AO, Wobus CE, Lindesmith LC, Baric RS, Estes MK, Orchard RC, Baldridge MT, Wilen CB.   +17 more
europepmc   +9 more sources

Genome Sequences of Five Microviruses and a Murine Norovirus. [PDF]

Microbiol Resour Announc, 2021
Murine norovirus is a fecal-orally transmitted pathogen in mice which belongs to the same genus as human norovirus. Microviruses are bacteriophages with small circular single-stranded DNA genomes, belonging to the family Microviridae .
Zhou R, Yin J, Lu J, Wang J, Zhang W, Yang S, Wang X, Shen Q.   +7 more
europepmc   +4 more sources

Akt Plays Differential Roles during the Life Cycles of Acute and Persistent Murine Norovirus Strains in Macrophages. [PDF]

J Virol, 2022
Owusu IA, Passalacqua KD, Mirabelli C, Lu J, Young VL, Hosmillo M, Quaye O, Goodfellow I, Ward VK, Wobus CE.   +9 more
europepmc   +3 more sources

Murine Norovirus Infection Results in Anti-inflammatory Response Downstream of Amino Acid Depletion in Macrophages. [PDF]

J Virol, 2021
Brocard M, Lu J, Hall B, Borah K, Moller-Levet C, Georgana I, Sorgeloos F, Beste DJV, Goodfellow IG, Locker N.   +9 more
europepmc   +2 more sources

Antibody Production Remains Intact Despite Loss of Bone Marrow B cells in Murine Norovirus Infected Stat1^-/- Mice. [PDF]

Comp Med, 2021
Eldridge DE, Hsu CC.
europepmc   +3 more sources

CD300lf Conditional Knockout Mouse Reveals Strain-Specific Cellular Tropism of Murine Norovirus. [PDF]

J Virol, 2021
Graziano VR, Graziano VR, Alfajaro MM, Schmitz CO, Filler RB, Strine MS, Wei J, Hsieh LL, Baldridge MT, Nice TJ, Lee S, Orchard RC, Wilen CB.   +12 more
europepmc   +3 more sources

Pathology caused by persistent murine norovirus infection [PDF]

Journal of General Virology, 2013
Subclinical infection of murine norovirus (MNV) was detected in a mixed breeding group of WT and Stat1 −/− mice with no outward evidence of morbidity or mortality. Investigations revealed the presence of an attenuated MNV variant that did not cause cytopathic effects in RAW264.7 cells or death in Stat1 −/− mice ...
Amita Shortland, James Chettle, Joy Archer, Kathryn J. Wood, Dalan Bailey, Ian Goodfellow, Barbara Blacklaws, Jonathan L. Heeney   +7 more
openalex   +5 more sources

Electron Micrographic Representations of Mechanisms of Action of Murine Norovirus on ATCC TIB-71 Cells and Level of Gene Expression

Advances in microbiology, 2023
Uchenna Iloghalu, Sara Miller, Akamu J. Ewunkem, Janak Raj Khatiwada, Shurrita S. Davis, Leonard Williams   +5 more
openalex   +3 more sources

Glucose Reduces Norovirus Binding to Enterobacter cloacae and Alters Gene Expression of Bacterial Surface Structures in a Growth Phase Dependent Manner

Viruses, 2022
Norovirus is the leading cause of acute viral gastroenteritis. Both human and murine noroviruses attach to commensal bacteria belonging to the mammalian gut flora, and binding levels are influenced by nutrients present in bacterial media.
Kendall J. Long, Chanel A. Mosby, Melissa K. Jones   +2 more
doaj   +1 more source

Development of a replication competent murine norovirus reporter system. [PDF]

PLoS Pathog
Caliciviruses are significant agricultural and human pathogens that are poorly understood due to the dearth of molecular tools, including reporter systems. We report the development of a robust luciferase-based reporter system for a model calicivirus, murine norovirus (MNoV).
Olson MC, Pierce LR, Orchard RC.
europepmc   +4 more sources