Results 41 to 50 of about 13,727 (226)

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine–Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2

open access: yesmBio, 2017
The Norovirus genus contains important human pathogens, but the role of host pathways in norovirus replication is largely unknown. Murine noroviruses provide the opportunity to study norovirus replication in cell culture and in small animals.
Broc T. McCune   +10 more
doaj   +1 more source

Analysis of Synchronous and Asynchronous In Vitro Infections with Homologous Murine Norovirus Strains Reveals Time-Dependent Viral Interference Effects

open access: yesViruses, 2021
Viral recombination is a key mechanism in the evolution and diversity of noroviruses. In vivo, synchronous single-cell coinfection by multiple viruses, the ultimate prerequisite to viral recombination, is likely to be a rare event and delayed secondary ...
Louisa F. Ludwig-Begall   +7 more
doaj   +1 more source

Effect of food residues on norovirus survival on stainless steel surfaces. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: In households and food processing plants, minute food residues left behind from improper cleaning may influence the survivability of human norovirus on surfaces.
Hajime Takahashi   +4 more
doaj   +1 more source

Comparing Human Norovirus Surrogates: Murine Norovirus and Tulane Virus

open access: yesJournal of Food Protection, 2013
Viral surrogates are widely used by researchers to predict human norovirus behavior. Murine norovirus (MNV) is currently accepted as the best surrogate and is assumed to mimic the survival and inactivation of human noroviruses. Recently, a new calicivirus, the Tulane virus (TV), was discovered, and its potential as a human norovirus surrogate is being
Kirsten A, Hirneisen, Kalmia E, Kniel
openaire   +2 more sources

Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]

open access: yes, 2017
Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David   +8 more
core   +1 more source

Unraveling the interplay between norovirus infection, gut microbiota, and novel antiviral approaches: a comprehensive review

open access: yesFrontiers in Microbiology, 2023
Norovirus infection is a leading cause of acute gastroenteritis worldwide and can also cause harmful chronic infections in individuals with weakened immune systems.
Geng-Hao Bai   +8 more
doaj   +1 more source

Expression of Ifnlr1 on intestinal epithelial cells is critical to the antiviral effects of IFN-lambda against norovirus and reovirus [PDF]

open access: yes, 2017
Lambda interferon (IFN-λ) has potent antiviral effects against multiple enteric viral pathogens, including norovirus and rotavirus, in both preventing and curing infection. Because the intestine includes a diverse array of cell types, however, the cell(s)
Baldridge, Megan T   +7 more
core   +2 more sources

Determination of Antiviral Mechanism of Centenarian Gut-Derived Limosilactobacillus fermentum Against Norovirus

open access: yesFrontiers in Nutrition, 2022
Although noroviruses are the causative agents of most non-bacterial foodborne disease outbreaks, effective antivirals are currently unavailable. Certain probiotic strains have been reported as active antivirals for norovirus infections, but their ...
Ying Li   +12 more
doaj   +1 more source

New proof-of-concept in viral inactivation: virucidal efficacy of 405 nm light against feline calicivirus as a model for norovirus decontamination [PDF]

open access: yes, 2016
The requirement for novel decontamination technologies for use in hospitals is ever present. One such system uses 405 nm visible light to inactivate microorganisms via ROS-generated oxidative damage.
Anderson, John G.   +7 more
core   +1 more source

NKT cells are responsible for the clearance of murine norovirus through the virus-specific secretory IgA pathway

open access: yesBiochemistry and Biophysics Reports, 2020
Norovirus infection cause epidemic nonbacterial gastroenteritis in patients. The immune mechanisms responsible for the clearance of virus are not completely understood. We examined whether NKT cells are effective against norovirus infection using CD1d KO
Hiroki Ishikawa   +7 more
doaj   +1 more source

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