Results 51 to 60 of about 13,538 (226)
Enhanced detection and study of murine norovirus-1 using a more efficient microglial cell line
Virology Journal, 2009 Background Human Noroviruses are the predominant cause of non-bacterial gastroenteritis worldwide. To facilitate prevention and control, a norovirus isolated from mice can provide a model to understand human noroviruses.
Lu Yuanan, Cao Shengbo, Cox Courtney
doaj +1 more source
A Dynamic Quantitative Microbial Risk Assessment for Norovirus in Potable Reuse System [PDF]
, 2019 This study describes the results of a dynamic quantitative microbial risk assessment (QMRA) for norovirus (NoV) that was used to evaluate the relative significance of foodborne, person-to-person, and person-to-sewage-to-person transmission pathways. This
Ahmad, Sajjad +3 more
core +2 more sources
Interferon-lambda: A potent regulator of intestinal viral infections [PDF]
, 2017 Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and ...
Baldridge, Megan T, Lee, Sanghyun
core +3 more sources
Wellcome Open Research, 2019 Background: Norovirus, also known as the winter vomiting bug, is the predominant cause of non-bacterial gastroenteritis worldwide. Disease control is predicated on a robust innate immune response during the early stages of infection.
Harriet V. Mears +5 more
doaj +1 more source
Comparing Human Norovirus Surrogates: Murine Norovirus and Tulane Virus
Journal of Food Protection, 2013 Viral surrogates are widely used by researchers to predict human norovirus behavior. Murine norovirus (MNV) is currently accepted as the best surrogate and is assumed to mimic the survival and inactivation of human noroviruses. Recently, a new calicivirus, the Tulane virus (TV), was discovered, and its potential as a human norovirus surrogate is being
Kalmia E. Kniel, Kirsten A. Hirneisen
openaire +2 more sources
The norovirus NS3 protein is a dynamic lipid- and microtubule-associated protein involved in viral RNA replication [PDF]
, 2017 Norovirus (NoV) infections are a significant health burden to society, yet the lack of reliable tissue culture systems has hampered the development of appropriate antiviral therapies.
Cotton, Ben T +6 more
core +2 more sources
Norovirus Attachment and Entry
Viruses, 2019 Human norovirus is a major human pathogen causing the majority of cases of viral gastroenteritis globally. Viral entry is the first step of the viral life cycle and is a significant determinant of cell tropism, host range, immune interactions, and ...
Vincent R. Graziano +2 more
doaj +1 more source
The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus [PDF]
Viruses, 2019 Cholesterol, an essential component of mammalian cells, is also an important factor in the replicative-cycles of several human and animal viruses. The oxysterol, 25-hydroxycholesterol, is produced from cholesterol by the enzyme, cholesterol 25-hydroxylase.
Ghada T. Shawli +3 more
openaire +5 more sources
The Effect of Malnutrition on Norovirus Infection
mBio, 2014 Human noroviruses are the primary cause of severe childhood diarrhea in the United States, and they are of particular clinical importance in pediatric populations in the developing world.
Danielle Hickman +10 more
doaj +1 more source
Communications Biology, 2022 NMR and native mass spectrometry reveal that the major capsid VP1 protein from murine and human norovirus exhibit distinct behaviors and are differentially regulated by the binding of glycochenodeoxycholic acid.
Robert Creutznacher +14 more
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