Results 51 to 60 of about 358,693 (195)

Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response. [PDF]

open access: yesPLoS Pathogens, 2012
Ubiquitin (Ub) is a vital regulatory component in various cellular processes, including cellular responses to viral infection. As obligate intracellular pathogens, viruses have the capacity to manipulate the ubiquitin (Ub) cycle to their advantage by ...
Jeffrey W Perry   +5 more
doaj   +1 more source

Dynamics in the murine norovirus capsid revealed by high-resolution cryo-EM. [PDF]

open access: goldPLoS Biol, 2020
Snowden JS   +5 more
europepmc   +3 more sources

Characterization of Ozone Disinfection of Murine Norovirus [PDF]

open access: yesApplied and Environmental Microbiology, 2010
ABSTRACT Despite the importance of human noroviruses (NoVs) in public health, little information concerning the effectiveness of ozone against NoVs is available. We determined the efficacy of ozone disinfection using murine norovirus (MNV) as a surrogate of human NoV.
Jung Eun Lee   +3 more
openaire   +3 more sources

Aerosolization and recovery of viable murine norovirus in an experimental setup. [PDF]

open access: yesSci Rep, 2020
AbstractNoroviruses are the major cause for viral acute gastroenteritis in the world. Despite the existing infection prevention strategies in hospitals, the disease continues to spread and causes extensive and numerous outbreaks. Hence, there is a need to investigate the possibility of airborne transmission of norovirus.
Alsved M   +5 more
europepmc   +5 more sources

Survival of Human Norovirus Surrogates in Water upon Exposure to Thermal and Non-Thermal Antiviral Treatments

open access: yesViruses, 2020
Human noroviruses are the leading cause of foodborne gastroenteritis worldwide and disease outbreaks have been linked to contaminated surface waters as well as to produce consumption.
Shu Zhu   +8 more
doaj   +1 more source

Heat-Denatured Lysozyme Inactivates Murine Norovirus as a Surrogate Human Norovirus [PDF]

open access: yesScientific Reports, 2015
AbstractHuman norovirus infects humans through the consumption of contaminated food, contact with the excrement or vomit of an infected person and through airborne droplets that scatter the virus through the air. Being highly infectious and highly viable in the environment, inactivation of the norovirus requires a highly effective inactivating agent ...
Miki Sato   +8 more
openaire   +2 more sources

Murine Norovirus: Additional Protocols for Basic and Antiviral Studies

open access: yesCurrent Protocols, 2023
Murine norovirus (MNV) is a positive‐sense, plus‐stranded RNA virus in the Caliciviridae family. Viruses in this family replicate in the intestine and are transmitted by the fecal‐oral route.
C. Wobus   +15 more
semanticscholar   +1 more source

Opposing Effects of Nitazoxanide on Murine and Human Norovirus [PDF]

open access: yesThe Journal of Infectious Diseases, 2017
_To the Editor_ Norovirus is a major cause of acute gastroenteritis worldwide, and chronic infections frequently occur in immunocompromised patients. However, no US Food and Drug Administration–approved specific medication is available for treating norovirus infection.
Qiuwei Pan   +3 more
openaire   +4 more sources

Noroviruses Co-opt the Function of Host Proteins VAPA and VAPB for Replication via a Phenylalanine–Phenylalanine-Acidic-Tract-Motif Mimic in Nonstructural Viral Protein NS1/2

open access: yesmBio, 2017
The Norovirus genus contains important human pathogens, but the role of host pathways in norovirus replication is largely unknown. Murine noroviruses provide the opportunity to study norovirus replication in cell culture and in small animals.
Broc T. McCune   +10 more
doaj   +1 more source

Effect of food residues on norovirus survival on stainless steel surfaces. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: In households and food processing plants, minute food residues left behind from improper cleaning may influence the survivability of human norovirus on surfaces.
Hajime Takahashi   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy