Results 61 to 70 of about 13,538 (226)

Critical role for interferon regulatory factor 3 (IRF-3) and IRF-7 in type i interferon-mediated control of murine norovirus replication [PDF]

, 2012
Human noroviruses (HuNoV) are the major cause of epidemic, nonbacterial gastroenteritis in the world. The short course of HuNoV-induced symptoms has implicated innate immunity in control of norovirus (NoV) infection.
Diamond, Michael S, Duan, Erning, Kambal, Amal, Lazear, Helen M, Schreiber, Robert D, Thackray, Larissa B, Virgin, Herbert W   +6 more
core   +2 more sources

Risk assessment for norovirus foodborne illness by raw oyster (Ostreidae) consumption and economic burden in Korea

Fisheries and Aquatic Sciences, 2022
The objective of this study was to evaluate the probability of norovirus foodborne illness by raw oyster consumption. One hundred fifty-six oyster samples were collected to examine the norovirus prevalence.
Yoonjeong Yoo, Hyemin Oh, Yewon Lee, Miseon Sung, Jeongeun Hwang, Ziwei Zhao, Sunho Park, Changsun Choi, Yohan Yoon   +8 more
doaj   +1 more source

Correction: MDA-5 Recognition of a Murine Norovirus

PLoS Pathogens, 2008
The fifth author's name is displayed incorrectly in the by-line and in the article citation. The author's correct attribution is Herbert W. Virgin. The correct citation is: McCartney SA, Thackray LB, Gitlin L, Gilfillan S, Virgin HW, et al. (2008) MDA-5 Recognition of a Murine Norovirus. PLoS Pathog 4(7): e1000108.
Stephen A. McCartney, Leonid Gitlin, Marco Colonna, Susan Gilfillan, Herbert W. Virgin, Larissa B. Thackray   +5 more
openaire   +3 more sources

Cysteine protease activation and apoptosis in Murine norovirus infection [PDF]

Virology Journal, 2009
AbstractBackgroundNoroviruses are the leading cause of viral gastroenteritis. Because a suitablein vitroculture system for the human virus has yet to be developed, many basic details of the infection process are unknown. Murine norovirus (MNV) serves as a model system for the study of norovirus infection. Recently it was shown that infection of RAW 264.
Brian Bothner, Khalil Ettayebi, Michele E. Hardy, Linnzi M Furman, Walid S. Maaty, Lena K. Petersen   +5 more
openaire   +3 more sources

Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses [PDF]

, 2013
Norovirus (NV) gastroenteritis is a major contributor to global morbidity and mortality, yet little is known about immune mechanisms leading to NV control. Previous studies using the murine norovirus (MNV) model have established a key role for T cells in
Artis, David, Dolfi, Douglas V, Mansfield, Kathleen, Monticelli, Laurel A, Osborne, Lisa C, Sonnenberg, Gregory F, Tomov, Vesselin T, Virgin, Herbert W, Wherry, E. John   +8 more
core   +2 more sources

Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins

Viruses, 2019
Murine norovirus (MNV) viral protein genome-linked (VPg) manipulates the cell cycle to induce a G0/G1 arrest and gain a beneficial replication environment.
Alice McSweeney, Colin Davies, Vernon K. Ward   +2 more
doaj   +1 more source

Inactivation of murine norovirus by chemical biocides on stainless steel [PDF]

BMC Infectious Diseases, 2009
Abstract Background Human norovirus (NoV) causes more than 80% of nonbacterial gastroenteritis in Europe and the United States. NoV transmission via contaminated surfaces may be significant for the spread of viruses.
Peter Goroncy-Bermes, Eike Steinmann, Jochen Steinmann, Jörg Steinmann, Dajana Paulmann, Birte Bischoff, Thomas Magulski, Britta Becker   +7 more
openaire   +4 more sources

The murine norovirus core subgenomic RNA promoter consists of a stable stem-loop that can direct accurate initiation of RNA synthesis. [PDF]

, 2014
UNLABELLED: All members of the Caliciviridae family of viruses produce a subgenomic RNA during infection. The subgenomic RNA typically encodes only the major and minor capsid proteins, but in murine norovirus (MNV), the subgenomic RNA also encodes the ...
Bailey, Dalan, Chaudhry, Yasmin, Goodfellow, Ian, Kao, C Cheng, Karakasiliotis, Ioannis, Lin, Xiaoyan, Thorne, Lucy, Vashist, Surender, Yunus, Muhammad Amir, Zhang, Guo   +9 more
core   +1 more source

Murine norovirus infection does not cause major disruptions in the murine intestinal microbiota [PDF]

Microbiome, 2013
Abstract Background Murine norovirus (MNV) is the most common gastrointestinal pathogen of research mice and can alter research outcomes in biomedical mouse models of inflammatory bowel disease (IBD). Despite indications that an altered microbiota is a risk factor for IBD, the response of the murine intestinal ...
Nelson, Adam M, Elftman, Michael D, Pinto, Amelia K, Baldridge, Megan, Hooper, Patrick, Kuczynski, Justin, Petrosino, Joseph F, Young, Vincent B, Wobus, Christiane E   +8 more
openaire   +4 more sources

Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation

eLife, 2019
Knowledge of the host factors required for norovirus replication has been hindered by the challenges associated with culturing human noroviruses. We have combined proteomic analysis of the viral translation and replication complexes with a CRISPR screen,
Myra Hosmillo, Jia Lu, Michael R McAllaster, James B Eaglesham, Xinjie Wang, Edward Emmott, Patricia Domingues, Yasmin Chaudhry, Tim J Fitzmaurice, Matthew KH Tung, Marc Dominik Panas, Gerald McInerney, Nicolas Locker, Craig B Wilen, Ian G Goodfellow   +14 more
doaj   +1 more source