Ultrasensitive Colorimetric Detection of Murine Norovirus Using NanoZyme Aptasensor [PDF]
Analytical Chemistry, 2019 Human norovirus (NoV) remains the most common cause of viral gastroenteritis and the leading cause of viral foodborne outbreaks globally. NoV is highly pathogenic with an estimated median viral infective dose (ID50) ranging from 18 to 1015 genome copies.
Pabudi Weerathunge +7 more
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Murine Norovirus: Additional Protocols for Basic and Antiviral Studies
Current Protocols, 2023 AbstractMurine norovirus (MNV) is a positive‐sense, plus‐stranded RNA virus in the Caliciviridae family. Viruses in this family replicate in the intestine and are transmitted by the fecal‐oral route. MNV is related to the human noroviruses, which cause the majority of nonbacterial gastroenteritis worldwide.
Wobus, Christiane E. +15 more
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Critical role for interferon regulatory factor 3 (IRF-3) and IRF-7 in type i interferon-mediated control of murine norovirus replication [PDF]
, 2012 Human noroviruses (HuNoV) are the major cause of epidemic, nonbacterial gastroenteritis in the world. The short course of HuNoV-induced symptoms has implicated innate immunity in control of norovirus (NoV) infection.
Diamond, Michael S +6 more
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The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus [PDF]
Viruses, 2019 Cholesterol, an essential component of mammalian cells, is also an important factor in the replicative-cycles of several human and animal viruses. The oxysterol, 25-hydroxycholesterol, is produced from cholesterol by the enzyme, cholesterol 25-hydroxylase.
Ghada T. Shawli +3 more
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Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses [PDF]
, 2013 Norovirus (NV) gastroenteritis is a major contributor to global morbidity and mortality, yet little is known about immune mechanisms leading to NV control. Previous studies using the murine norovirus (MNV) model have established a key role for T cells in
Artis, David +8 more
core +2 more sources
Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins
Viruses, 2019 Murine norovirus (MNV) viral protein genome-linked (VPg) manipulates the cell cycle to induce a G0/G1 arrest and gain a beneficial replication environment.
Alice McSweeney +2 more
doaj +1 more source
Efficacy of Cinnamaldehyde Against Enteric Viruses and Its Activity After Incorporation Into Biodegradable Multilayer Systems of Interest in Food Packaging [PDF]
, 2016 Cinnamaldehyde (CNMA), an organic compound that gives cinnamon its flavor and odor, was investigated for its virucidal activity on norovirus surrogates, murine norovirus (MNV) and feline calicivirus (FCV), and hepatitis A virus (HAV).
Aznar, Rosa +6 more
core +1 more source
Fisheries and Aquatic Sciences, 2022 The objective of this study was to evaluate the probability of norovirus foodborne illness by raw oyster consumption. One hundred fifty-six oyster samples were collected to examine the norovirus prevalence.
Yoonjeong Yoo +8 more
doaj +1 more source
Discovery of murine norovirus receptor
Uirusu, 2017 Norovirus is the leading cause of acute gastroenteritis worldwide. Since the discovery of human norovirus (HuNoV), an efficient and reproducible norovirus replication system has not been established in cultured cells. Although limited amounts of virus particles can be produced when the HuNoV genome is directly transfected into cells, the HuNoV cycle of
openaire +3 more sources
, 2015 Norovirus is one of the most common causes of acute viral gastroenteritis. The virus is spread via the fecal-oral route, most commonly from infected food and water, but several outbreaks have originated from contamination of surfaces with infectious ...
Keevil, C William +2 more
core +1 more source