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Discovery of VU6016235: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM). [PDF]

open access: yesACS Chem Neurosci
Engers JL   +17 more
europepmc   +1 more source

Weight Gain With Advancing Age Is Controlled by the Muscarinic Acetylcholine Receptor M4 in Male Mice.

open access: yesEndocrinology
Takahashi T   +7 more
europepmc   +1 more source

Discovery of Pre-Clinical Candidate <b>VU6008055</b>/<b>AF98943</b>: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust In Vivo Efficacy. [PDF]

open access: yesACS Chem Neurosci
Engers JL   +26 more
europepmc   +1 more source

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