Results 181 to 190 of about 28,480 (301)

M3 Muscarinic Acetylcholine Receptor Expression Confers Differential Cholinergic Modulation to Neurochemically Distinct Hippocampal Basket Cell Subtypes [PDF]

, 2010
Christian A. Cea-Del Rio, J. Josh Lawrence, Ludovic Tricoire, Ferenc Erdélyi, Gábor Szabó, Chris J. McBain   +5 more
openalex   +1 more source

Rooibos (Aspalathus linearis) extract, containing eriodictyol-6-C-β-d-glucoside as the active component, stimulates exocrine glands via the M3 muscarinic acetylcholine receptor

Journal of Functional Foods, 2019
We previously discovered that rooibos extract activates the M3 muscarinic acetylcholine receptor (M3R), a key component of exocrine secretion. In this study, we examined the rooibos extract for active components in vitro and monitored its fast-acting ...
Saori Nishimachi, Takao Iwai, Yoshitaka Nakamura, Kanako Yuyama-Masuda, Takuya Tsutsui, Noriyuki Monoi, Akira Uchiyama, Seiji Nakamura   +7 more
doaj  

Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors [PDF]

, 2014
Pavel Michal, Esam E. El‐Fakahany, Vladimı́r Doležal   +2 more
openalex   +1 more source

Interaction of lithocholylcholine, a newly-synthesized chimera of acetylcholine and conjugated lithocholic acid, with M3 muscarinic receptors on cho cells

, 2000
Kunrong Cheng, Piotr Zimniak, Jean‐Pierre Raufman   +2 more
openalex   +1 more source

Regulation of acetylcholine release from guinea-pig bladder urothelial cells - potential role in bladder filling sensations [PDF]

, 2014
Fry, C. H., McLatchie, L. M., Young, John S.   +2 more
core   +1 more source

Muscarinic Acetylcholine Receptor M3 Mutation Causes Urinary Bladder Disease and a Prune-Belly-like Syndrome.

American Journal of Human Genetics, 2011
S. Weber, H. Thiele, S. Mir, M. Toliat, B. Sozeri, H. Reutter, Markus Draaken, M. Ludwig, J. Altmüller, P. Frommolt, H. Stuart, P. Ranjzad, N. Hanley, Rachel E. Jennings, W. Newman, D. Wilcox, U. Thiel, K. Schlingmann, R. Beetz, P. Hoyer, M. Konrad, F. Schaefer, P. Nürnberg, A. Woolf   +23 more
semanticscholar   +1 more source

Intradermal Cholinergic Agonists Induce Itch-Associated Response via M3 Muscarinic Acetylcholine Receptors in Mice

, 2002
Takayuki Miyamoto, Hiroshi Nojima, Yasushi Kuraishi   +2 more
openalex   +1 more source

Muscarinic cannabinoid suppression of excitation, a novel form of coincidence detection

Pharmacological Research
Δ9-tetrahydrocannabinol (THC), the chief psychoactive ingredient of cannabis, acts in the brain primarily via cannabinoid CB1 receptors. These receptors are implicated in several forms of synaptic plasticity – depolarization-induced suppression of ...
Michaela Dvorakova, Ken Mackie, Alex Straiker   +2 more
doaj  

Vagus nerve stimulation as a modulator of feedforward and feedback neural transmission [PDF]

arXiv
Vagus nerve stimulation (VNS) has emerged as a promising therapeutic intervention across various neurological and psychiatric conditions, including epilepsy, depression, and stroke rehabilitation; however, its mechanisms of action on neural circuits remain incompletely understood.
arxiv  

CreoPep: A Universal Deep Learning Framework for Target-Specific Peptide Design and Optimization [PDF]

arXiv
Target-specific peptides, such as conotoxins, exhibit exceptional binding affinity and selectivity toward ion channels and receptors. However, their therapeutic potential remains underutilized due to the limited diversity of natural variants and the labor-intensive nature of traditional optimization strategies. Here, we present CreoPep, a deep learning-
arxiv