Results 231 to 240 of about 27,064 (276)

Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M₂ Muscarinic Acetylcholine Receptor. [PDF]

ACS Med Chem Lett
Szabó R, Szepesi Kovács D, Kiss DJ, Yazdi ZN, Tóth AD, Brea J, Loza MI, Meszéna D, Wittner L, Ulbert I, Volk B, Hunyady L, Keserű GM.   +12 more
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Enhancing remyelination in multiple sclerosis via M1 muscarinic acetylcholine receptor. [PDF]

Mol Pharmacol
Chen K, Park E, Abd-Elrahman KS.
europepmc   +1 more source

Evaluation of the anti-spasmodic activity of essential oils of Ammodaucus leucotrichus fruits and its main chemical component "perillaldehyde" on intestinal smooth muscle contractions of rodents: ex vivo and in silico approaches. [PDF]

Front Chem
Karim A, Marghich M, Amrani O, Addous A, Malek S, Beyi L, Harit T, Aldisi D, Aboul-Soud MAM, Giesy JP, Aziz M.   +10 more
europepmc   +1 more source

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Muscarinic Acetylcholine Receptor M3

Definitions, 2020

semanticscholar   +2 more sources

Computer‐aided design of muscarinic acetylcholine receptor M3 inhibitors: Promising compounds among trifluoromethyl containing hexahydropyrimidinones/thiones

Molecular Informatics, 2023
The new high selective mAChRs M3 inhibitors with IC50 in nanomolecular ranges, which can be the prototypes for effective COPD and asthma treatment drugs, were discovered with computational approaches among trifluoromethyl containing ...
A. Nyporko, O. Tsymbalyuk, I. Voiteshenko, S. Starosyla, Mykola V. Protopopov, V. Bdzhola   +5 more
semanticscholar   +1 more source

Muscarinic acetylcholine receptor M3 in proliferation and perineural invasion of cholangiocarcinoma cells.

Hepatobiliary & Pancreatic Diseases International, 2012
Cholangiocarcinoma, a type of malignant tumor, originates from epithelial cells of the bile duct. Perineural invasion is common path for cholangiocarcinoma metastasis, and it is highly correlated with postoperative recurrence and poor prognosis. It has been reported that muscarinic acetylcholine receptor M3 (mAChR M3) is widely expressed in digestive ...
Yujie Feng, Bingyuan Zhang, R. Yao, Yun Lu   +3 more
semanticscholar   +3 more sources

M3 muscarinic acetylcholine receptor in cardiology and oncology.

International Journal of Cardiology, 2014
S. Patane'
semanticscholar   +3 more sources

m3 Muscarinic Acetylcholine Receptor Regulation in the Airway

American Journal of Respiratory Cell and Molecular Biology, 2002
The m3 muscarinic acetylcholine receptor (m3 mAChR) plays an important role in airway function by mediating the effects of acetylcholine on multiple airway cell types. m3 mAChRs expressed in airway smooth muscle (ASM) cells promote increased ASM tension, and, therefore, airway narrowing, in response to acetylcholine release from postganglionic ...
Charlotte K, Billington, Raymond B, Penn
openaire   +2 more sources

Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean

Nature, 2001
Members of the muscarinic acetylcholine receptor family (M1-M5) have central roles in the regulation of many fundamental physiological functions. Identifying the specific receptor subtype(s) that mediate the diverse muscarinic actions of acetylcholine is of considerable therapeutic interest, but has proved difficult primarily because of a lack of ...
M, Yamada, T, Miyakawa, A, Duttaroy, A, Yamanaka, T, Moriguchi, R, Makita, M, Ogawa, C J, Chou, B, Xia, J N, Crawley, C C, Felder, C X, Deng, J, Wess   +12 more
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