Results 261 to 270 of about 51,230 (302)

Evidence for M2 Muscarinic Receptor Antagonist Delay of Myopia Development Through Activation of Kir3.4 Channel in the Retina of Guinea Pigs. [PDF]

Invest Ophthalmol Vis Sci
Zhou H, Zhou G, Yang Q, Niu J, Wang R, Liu H, Hou S, Bi H, Liao X.   +8 more
europepmc   +1 more source

Burden of Exacerbations in Patients Newly Initiating an Inhaled Regimen for COPD: A Claims Analysis. [PDF]

Int J Chron Obstruct Pulmon Dis
Sethi S, Wan ES, Tejwani V, Lamprey C, Aggarwal K, Dixon A, Pan Y, Siddharthan T.   +7 more
europepmc   +1 more source

Factors influencing treatment escalation from long-acting muscarinic antagonist monotherapy to triple therapy in patients with COPD: a retrospective THIN-database analysis. [PDF]

Int J Chron Obstruct Pulmon Dis, 2018
Hurst JR, Dilleen M, Morris K, Hills S, Emir B, Jones R.   +5 more
europepmc   +1 more source

Comparison of clinical outcome of COPD with asthma-like feature with different inhalation therapies: a real-world study in the prospective RealDTC cohort. [PDF]

BMC Pulm Med
Lin L, Cheng W, Song Q, Li T, Liu C, Zhang P, Zeng Y, Deng D, Yu Z, Chen Y, Chen P.   +10 more
europepmc   +1 more source

Role of the cholinergic system in the psychopathology and treatment of schizophrenia: a protocol for a scoping review. [PDF]

Front Psychiatry
Haczkiewicz M, Hylén U, Msghina M.
europepmc   +1 more source

Evaluating digital adherence support in asthma: the ADITION non-interventional study. [PDF]

ERJ Open Res
Woehrle H, Driemert J, Jerrentrup L, Schiefer C, Bushart G, Schwab Sauerbeck I.   +5 more
europepmc   +1 more source

Muscarinic receptor agonists and antagonists [PDF]

Expert Opinion on Therapeutic Patents, 1999
Although four different subtypes of the muscarinic acetylcholine (ACh) receptor with functional correlates are known to exist (function for M5 is still unclear), all muscarinic agonists and antagon...
Darius P. Zlotos, Wiebke Bender, Ulrike Holzgrabe   +2 more
openaire   +1 more source

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Role of muscarinic antagonists in asthma therapy

Expert Review of Respiratory Medicine, 2017
Higher parasympathetic tone has been reported in asthmatics. In general, cholinergic contractile tone is increased by airway inflammation associated with asthma. Nevertheless, the role of muscarinic antagonists for the treatment of asthma has not yet been clearly defined.
CAZZOLA, MARIO, Ora, J, ROGLIANI, PAOLA, Matera, Mg   +3 more
openaire   +5 more sources

Selective muscarinic receptor antagonists

Trends in Pharmacological Sciences, 1984
to ex- plain the anomalous binding of cholin- ergic agonists to brain receptors~ were later demonstrated with the seEective muscarinic antagonist, pirenzepine 2. Interestingly, the search for selective antagonists, which usually follows the acceptance of a concept, antedated by many years the notion of heterogeneity of rmecarinic receptors. Intuitively
R. Hammer, A. Giachetti
openaire   +2 more sources