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[Antianaphylactic effects of muscarinic antagonists].
Eksperimental'naia i klinicheskaia farmakologiia, 2010The study was carried out on color guinea pigs, in which anaphylactic shock was induced by sensitizing and challenging doses of normal horse serum (HS). Administration of atropine, ipratropium, or ipratropium in combination with neostigmine led to reduction of sensitizing effect of HS: anaphylactic index was decreased up to (2.2 - 2.4) +/- 0.1 ...
G I, Nezhinskaia +2 more
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Muscarinic Agonists and Antagonists: Effects on the Urinary Bladder
2011Voiding of the bladder is the result of a parasympathetic muscarinic receptor activation of the detrusor smooth muscle. However, the maintenance of continence and a normal bladder micturition cycle involves a complex interaction of cholinergic, adrenergic, nitrergic and peptidergic systems that is currently little understood.
Sellers, Donna J., Chess-Williams, Russ
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Muscarinic Receptor Antagonists
Pulmonary Pharmacology & Therapeutics, 1999N, Watson, R M, Eglen
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THE INTERACTION OF NICOTINIC RECEPTOR ANTAGONISTS AT MUSCARINIC RECEPTORS
Clinical and Experimental Pharmacology and Physiology, 1987SUMMARY1. The interaction of some neuromuscular blocking drugs such as gallamine, pancuronium and stercuronium with muscarinic receptors has several features which distinguish these compounds from competitive antagonists in functional and binding studies.2. They also differentiate between muscarinic receptors and may produce effects on ion channels.
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Selective muscarinic antagonists as bronchodilators.
Agents and actions. Supplements, 1992The non-selective muscarinic antagonist ipratropium is widely used as bronchodilator. Due to its pharmacokinetic properties this drug, after inhalation, acts only locally on the airways and no unwanted anticholinergic side-effects are observed. Another approach is the use of selective muscarinic antagonists. Based on their selectivity for M3- and/or M1-
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The Binding of Antagonists to Brain Muscarinic Receptors
Molecular Pharmacology, 1978E C, Hulme +3 more
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