Results 301 to 310 of about 2,360,825 (374)
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Annual Review of Pharmacology and Toxicology, 1990
In 1914, Sir Henry Dale provided the basis for the classical and comfortable definition of muscarinic and nicotinic acetylcholine receptors: Muscarinic receptors are selectively activated by muscarine and blocked by atropine; nicotinic receptors are activated by nicotine and blocked by curare.
Nigel J. M. Birdsall +2 more
openaire +5 more sources
In 1914, Sir Henry Dale provided the basis for the classical and comfortable definition of muscarinic and nicotinic acetylcholine receptors: Muscarinic receptors are selectively activated by muscarine and blocked by atropine; nicotinic receptors are activated by nicotine and blocked by curare.
Nigel J. M. Birdsall +2 more
openaire +5 more sources
Muscarinic Receptor Trafficking [PDF]
, 2011 Knowledge of the mechanisms responsible for the trafficking of neurotransmitter receptors away from the cell surface is of obvious importance in understanding what regulates their expression and function. This chapter will focus on the mechanisms responsible for the internalization and degradation of muscarinic receptors.
Neil M. Nathanson, Cindy Reiner
openaire +2 more sources
MUSCARINIC RECEPTOR DIFFERENTIATION
Clinical and Experimental Pharmacology and Physiology, 1989SUMMARY1. Several selective antagonists are available to differentiate between muscarinic receptors.2. Further subdivision of M1 and M2 muscarinic receptors appears possible and is supported by studies with cloned receptors.3. Reasons for differences between affinity constants determined in functional and binding studies and whether receptor subtypes ...
S Darroch +2 more
openaire +3 more sources
Muscarinic receptors in pineal
Life Sciences, 1980Abstract The presence of muscarinic receptors in sheep and rat pineals was detected by binding of [ 3 H]quinuclidinyl benzilate ([ 3 H]QNB), a potent and specific muscarinic antagonist. [ 3 H]QNB binding to sheep pineal membrane resuspensions was saturable and reversible, with a rate constant for association at 37°C of 6×10 8 M −1 min −1 and a rate ...
Richard L. Taylor +2 more
openaire +3 more sources
Muscarinic acetylcholine receptor
Progress in Neurobiology, 1978ABSTRACT Muscarinic acetylcholine receptors from rat cerebral cortex and small intestine were studied by the high affinity and high specific activity antagonists 3 H-3-quinuclidinyl benzilate (3-QNB) (29.4 Ci/mmol) and 3 H-N-methyl-4-piperidinyl benzilate (4-NMPB) (55.4 Ci/mmol).
Edith Heilbronn, Tamas Bartfai
openaire +4 more sources
Pharmacological approaches to targeting muscarinic acetylcholine receptors.
Recent Patents on CNS Drug Discovery, 2014The presence of cholinergic system markers and muscarinic receptor subtypes in several tissues also of nonneuronal type has been largely demonstrated. Acetylcholine, synthesized in the nervous system, can locally contribute to modulate cell proliferation,
C. Matera, A. Tata
semanticscholar +1 more source
Muscarinic M₃ receptors contribute to allergen-induced airway remodeling in mice.
American Journal of Respiratory Cell and Molecular Biology, 2014Asthma is a chronic obstructive airway disease, characterized by inflammation and remodeling. Acetylcholine contributes to symptoms by inducing bronchoconstriction via the muscarinic M3 receptor.
L. Kistemaker +8 more
semanticscholar +1 more source