Results 91 to 100 of about 1,945,583 (386)

Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik, Benjamin Barthel, Nanna R. Andersen, Sofie V. Skriver, Alan J. Russell, John Vissing   +5 more
wiley   +1 more source

Impact of contraction intensity and ankle joint angle on calf muscle fascicle length and pennation angle during isometric and dynamic contractions

Scientific Reports
During muscle contraction, not only are the fascicles shortening but also the pennation angle changes, which leads to a faster contraction of the muscle than of its fascicles. This phenomenon is called muscle gearing, and it has a direct influence on the
Corinna Coenning, Volker Rieg, Tobias Siebert, Veit Wank   +3 more
doaj   +1 more source

Stable isotope-labeled carnitine reveals its rapid transport into muscle cells and acetylation during contraction

Heliyon, 2023
Carnitine plays multiple roles in skeletal muscle metabolism, including fatty acid transport and buffering of excess acetyl-CoA in the mitochondria. The skeletal muscle cannot synthesize carnitine; therefore, carnitine must be taken up from the blood ...
Yasuro Furuichi, Naoko Goto-Inoue, Saki Uchida, Shun Masuda, Yasuko Manabe, Nobuharu L. Fujii   +5 more
doaj  

Exaggerated Pressor Response in Relation to Attenuated Muscle Temperature Response during Contraction in Ischemic Heart Failure

Frontiers in Physiology, 2012
It is known that muscle temperature (Tm) increases with exercise. The purpose of this study was to examine if contraction-induced increase in Tm was altered in rats with heart failure (HF) induced by chronic myocardial infraction (MI) as compared with ...
Jianhua eLi, Zhaohui eGao, Jian eLu, Jihong eXing   +3 more
doaj   +1 more source

Effect of Uni and Bilateral High-Intensity Sustained Isometric Contraction Exercise on Fatigue Related Changes in Quadriceps Femoris

Baltic Journal of Sport and Health Sciences, 2020
Background. It is well established that different types of exercise can provide central and peripheral fatigue. However, there are conflicting findings in the literature, and a consensus has not been reached regarding the different patterns of different ...
Giedrė Jurgelaitienė, Andrius Šatas, Dalia Mickevičienė, Albertas Skurvydas   +3 more
doaj   +1 more source

Insights into muscle metabolic energetics: Modelling muscle-tendon mechanics and metabolic rates during walking across speeds [PDF]

arXiv, 2023
Prior studies have produced models to predict metabolic rates based on experimental observations of isolated muscle contraction from various species. Such models can provide reliable predictions of metabolic rates in humans if muscle properties and control are accurately modeled.
arxiv  

The Central Nervous System (CNS)-independent Anti-bone-resorptive Activity of Muscle Contraction and the Underlying Molecular and Cellular Signatures*

Journal of Biological Chemistry, 2013
Background: Mechanisms by which muscle regulates bone are poorly understood. Results: Electrically stimulated muscle contraction reversed elevations in bone resorption and increased Wnt signaling in bone-derived cells after spinal cord transection ...
W. Qin, Li Sun, Jay J Cao, Yuanzhen Peng, L. Collier, Yong Wu, G. Creasey, Jianhua Li, Yiwen Qin, J. Jarvis, W. Bauman, M. Zaidi, C. Cardozo   +12 more
semanticscholar   +1 more source

Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Deep brain stimulation offers a unique opportunity to record neural activity of the basal ganglia. While much work in dystonia has focused on the globus pallidus internus, expanding research to investigate subthalamic nucleus (STN) activity in various dystonia types is critical to provide a comprehensive understanding of dystonia ...
Zhu Guan‐Yu, Yin Zi‐Xiao, Chen Ying‐Chuan, Timon Merk, Thomas Binns, Ma Ruo‐Yu, Du Ting‐Ting, Liu Yu‐Ye, Xie Hu‐Tao, Shi Lin, Yang An‐Chao, Meng Fan‐Gang, Wolf‐Julian Neumann, Andrea A. Kühn, Zhang Jian‐Guo   +14 more
wiley   +1 more source

Detecting muscle activation using ultrasound speed of sound inversion with deep learning [PDF]

arXiv, 2019
Functional muscle imaging is essential for diagnostics of a multitude of musculoskeletal afflictions such as degenerative muscle diseases, muscle injuries, muscle atrophy, and neurological related issues such as spasticity. However, there is currently no solution, imaging or otherwise, capable of providing a map of active muscles over a large field of ...
arxiv  

The bionic neural network for external simulation of human locomotor system [PDF]

arXiv, 2023
Muscle forces and joint kinematics estimated with musculoskeletal (MSK) modeling techniques offer useful metrics describing movement quality. Model-based computational MSK models can interpret the dynamic interaction between the neural drive to muscles, muscle dynamics, body and joint kinematics, and kinetics.
arxiv