Results 121 to 130 of about 2,186,751 (353)

Calcium regulation of muscle contraction

open access: yesBiophysical Journal, 1975
Calcium triggers contraction by reaction with regulatory proteins that in the absence of calcium prevent interaction of actin and myosin. Two different regulatory systems are found in different muscles. In actin-linked regulation troponin and tropomyosin regulate actin by blocking sites on actin required for complex formation with myosin; in myosin ...
openaire   +3 more sources

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim   +10 more
wiley   +1 more source

Sensitivity to Hand Path Curvature during Reaching [PDF]

open access: yes, 2003
People optimize reaching to make straight and smooth movements. We performed experiments characterizing human sensitivity to hand path deviations from a straight reach. Vision of the arm was blocked.
Lillis, Kyle P., Scheidt, Robert A.
core   +1 more source

The Work of Titin Protein Folding as a Major Driver in Muscle Contraction.

open access: yesAnnual Review of Physiology, 2018
Edward C. Eckels   +3 more
semanticscholar   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

open access: yesAdvanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz   +2 more
wiley   +1 more source

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