Results 11 to 20 of about 1,945,583 (386)
Phenotypic continuum of NFU1‐related disorders
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2025-2035, December 2022., 2022 Abstract Bi‐allelic variants in Iron–Sulfur Cluster Scaffold (NFU1) have previously been associated with multiple mitochondrial dysfunctions syndrome 1 (MMDS1) characterized by early‐onset rapidly fatal leukoencephalopathy. We report 19 affected individuals from 10 independent families with ultra‐rare bi‐allelic NFU1 missense variants associated with a
Rauan Kaiyrzhanov +45 more
wiley +1 more source
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022 Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh +5 more
wiley +1 more source
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022 Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee +16 more
wiley +1 more source
BMC Neuroscience, 2020 Background During voluntary muscle contraction, sensory information induced by electrostimulation of the nerves supplying the contracting muscle is inhibited and the somatosensory evoked potentials (SEPs) amplitude decreases.
Terumasa Takahara +3 more
doaj +1 more source
Nihon Kikai Gakkai ronbunshu, 2023 Recently, the movement and muscle usage principles have been elucidated by analyzing the kinematic and dynamic parameters of various body parts during movements and exercises.
Toru TSUMUGIWA +2 more
doaj +1 more source
Vascular smooth muscle contraction in hypertension
Cardiovascular Research, 2018 Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia, and chronic kidney disease.
R. Touyz +6 more
semanticscholar +1 more source
A Piezoresistive Sensor to Measure Muscle Contraction and Mechanomyography
Italian National Conference on Sensors, 2018 Measurement of muscle contraction is mainly achieved through electromyography (EMG) and is an area of interest for many biomedical applications, including prosthesis control and human machine interface. However, EMG has some drawbacks, and there are also
D. Esposito +6 more
semanticscholar +1 more source
Glycolysis Mediated Sarcoplasmic Reticulum Ca Signal Regulates Mitochondria Ca during Skeletal Muscle Contraction [PDF]
운동과학, 2017 PURPOSE This study was to investigate the Glycolysis mediated sarcoplasmic reticulum (SR) Ca2+ signal regulates mitochondria Ca2+ during skeletal muscle contraction by using glycolysis inhibitor.
Dae-Ryoung Park
doaj +1 more source
The Multi-Scale, Three-Dimensional Nature of Skeletal Muscle Contraction.
Physiology, 2019 Muscle contraction is a three-dimensional process, as anyone who has observed a bulging muscle knows. Recent studies suggest that the three-dimensional nature of muscle contraction influences its mechanical output.
T. Roberts +7 more
semanticscholar +1 more source
Biology, 2014 Myosin filaments in vertebrate striated muscle have a long roughly cylindrical backbone with cross-bridge projections on the surfaces of both halves except for a short central bare zone. In the middle of this central region the filaments are cross-linked
Pradeep K. Luther, John M. Squire
doaj +1 more source