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Considerations on muscle contraction
Journal of Electromyography and Kinesiology, 2002The independent force generator and the power-stroke cross-bridge model have dominated the thinking on mechanisms of muscular contraction for nearly the past five decades. Here, we review the evolution of the cross-bridge theory from its origins as a two-state model to the current thinking of a multi-state mechanical model that is tightly coupled with ...
Walter Herzog, Rachid Ait-Haddou
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Quarterly Reviews of Biophysics, 1969
As is well known, the memorable discovery of Galvani (1791) was followed by the development of two new fields of science, electrochemistry and electrophysiology. During the course of this development, the most remarkable feature of the original finding, i.e. ‘contraction of muscle induced by a piece of metal’, gradually came to be ignored.
I Otsuki, S Ebashi, M Endo
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As is well known, the memorable discovery of Galvani (1791) was followed by the development of two new fields of science, electrochemistry and electrophysiology. During the course of this development, the most remarkable feature of the original finding, i.e. ‘contraction of muscle induced by a piece of metal’, gradually came to be ignored.
I Otsuki, S Ebashi, M Endo
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Mysteries of Muscle Contraction
Journal of Applied Biomechanics, 2008According to the cross-bridge theory, the steady-state isometric force of a muscle is given by the amount of actin–myosin filament overlap. However, it has been known for more than half a century that steady-state forces depend crucially on contractile history. Here, we examine history-dependent steady-state force production in view of the cross-bridge
Venus Joumaa+3 more
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Muscle physiology and contraction
Surgery (Oxford), 2013Abstract Skeletal muscle has important metabolic functions but the focus of this article is to examine its ability to generate mechanical force. Adult skeletal muscle fibres are each innervated by a single branch of the axon arising from an α-motoneuron in the spinal cord. The α-motoneuron and all the fibres it innervates constitute a motor unit, and
Carolyn A. Greig+3 more
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Mechanism of muscle contraction
Technology and Health Care, 1993This work is the first attempt to propose a complex model of muscle contraction in which different aspects of the sarcomere shortening are collected into a logical entity. Proposed are some suggestions to answer some fundamental questions concerning the molecular mechanism of muscle contraction, such as the following: "of which part of the myosin ...
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Theories of Muscle Contraction
Journal of Structural Biology, 1995A survey of the mainstream theories in the modern study of the mechanism of muscle contraction is made, with particular emphasis placed on the experimental results which most influenced the progression of ideas. Starting with early elastic and viscoelastic theories of muscle contraction, a chronological organization is used to present, in detail, the ...
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Toward a theory of muscle contraction [PDF]
The general chemistry of muscle contraction was elucidated early on from test-tube reconstitutions of function:1, 2 Myosin and actin form an ATP-dissociable complex; myosin is an actin-modifiable ATPase, and the free energy of ATP hydrolysis “pays for” any work performed in contraction. The central structural feature of contraction was discovered later:
Gustavo Viniegra-Gonzalez+1 more
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Regulation of Muscle Contraction
1983The discovery of troponin (Ebashi and Kodama, 1965; cf. Ebashi et al., 1969) established the concept of regulation in muscle contraction and the term regulatory proteins (Maruyama and Ebashi, 1970). The absence of troponin or other specific regulatory proteins in molluscan striated muscle (Kendrick-Jones et al., 1970) suggested that the mode of ...
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Energy of Contraction in Muscle
Human Factors: The Journal of the Human Factors and Ergonomics Society, 1963A large body of the present day theory of production and absorption of work and heat by the contracting muscle is inferred from the experimental study of excised amphibian muscle at 0°. The question arises as to how well the results apply to in situ human muscles.
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Muscle contraction and muscle proteins [PDF]
There are three ways in which we can gain knowledge of the change of protein structure connected with muscular contraction. The first way is the observation of the contracting muscle itself. The changes of structural qualities and their time sequence have to be investigated. I take it that the excellent information which we have at present
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