Results 41 to 50 of about 521,340 (346)

Upper Limbs Muscle Co-contraction Changes Correlated With the Impairment of the Corticospinal Tract in Stroke Survivors: Preliminary Evidence From Electromyography and Motor-Evoked Potential

Frontiers in Neuroscience, 2022
ObjectiveIncreased muscle co-contraction of the agonist and antagonist muscles during voluntary movement is commonly observed in the upper limbs of stroke survivors. Much remain to be understood about the underlying mechanism.
Wenfei Sheng, Shijue Li, Jiangli Zhao, Yujia Wang, Zichong Luo, Wai Leung Ambrose Lo, Minghui Ding, Chuhuai Wang, Le Li   +8 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Regulation of gastric smooth muscle contraction via Ca2+-dependent and Ca2+-independent actin polymerization.

PLoS ONE, 2018
In gastrointestinal smooth muscle, acetylcholine induced muscle contraction is biphasic, initial peak followed by sustained contraction. Contraction is regulated by phosphorylation of 20 kDa myosin light chain (MLC) at Ser19, interaction of actin and ...
Sunila Mahavadi, Ancy D Nalli, Hongxia Wang, Derek M Kendig, Molly S Crowe, Vijay Lyall, John R Grider, Karnam S Murthy   +7 more
doaj   +1 more source

In vivo myograph measurement of muscle contraction at optimal length

BioMedical Engineering OnLine, 2007
Background Current devices for measuring muscle contraction in vivo have limited accuracy in establishing and re-establishing the optimum muscle length.
Ahmed Aminul, Pawlak Matthias, Karst Matthias, Weilbach Christian, Rahe-Meyer Niels, Piepenbrock Siegfried, Winterhalter Michael   +6 more
doaj   +1 more source

Regional Differences in Biceps Femoris Long Head Stiffness during Isometric Knee Flexion

Journal of Functional Morphology and Kinesiology, 2021
This study sought to investigate whether the stiffness of the biceps femoris long head differs between proximal and distal regions during isometric knee flexion at different contraction intensities and muscle lengths. Twelve healthy individuals performed
João R. Vaz, Tiago Neto, José Pedro Correia, Jorge Infante, Sandro R. Freitas   +4 more
doaj   +1 more source

Supraspinal Fatigue Impedes Recovery From a Low-Intensity Sustained Contraction in Old Adults [PDF]

, 2011
This study determined the contribution of supraspinal fatigue and contractile properties to the age difference in neuromuscular fatigue during and recovery from a low-intensity sustained contraction.
Hunter, Sandra K., Keller, Manda L., Schlinder-Delap, Bonnie, Yoon, Tejin   +3 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Localized Electrical Impedance Myography of the Biceps Brachii Muscle during Different Levels of Isometric Contraction and Fatigue

Sensors, 2016
This study assessed changes in electrical impedance myography (EIM) at different levels of isometric muscle contraction as well as during exhaustive exercise at 60% maximum voluntary contraction (MVC) until task failure.
Le Li, Henry Shin, Xiaoyan Li, Sheng Li, Ping Zhou   +4 more
doaj   +1 more source

Can real-time visual feedback during gait retraining reduce metabolic demand for individuals with transtibial amputation? [PDF]

, 2017
The metabolic demand of walking generally increases following lower extremity amputation. This study used real-time visual feedback to modify biomechanical factors linked to an elevated metabolic demand of walking in individuals with transtibial ...
Choi, Harmony S., Darter, Benjamin J., Esposito, Elizabeth R., Wilken, Jason M.   +3 more
core   +5 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source