Results 51 to 60 of about 490,179 (385)

Increased duration of co-contraction of medial knee muscles is associated with greater progression of knee osteoarthritis [PDF]

, 2015
Background: As knee osteoarthritis (OA) cannot be cured, treatments that slow structural disease progression are a priority. Knee muscle activation has a potential role in OA pathogenesis.
Bennell, Kim, Bowles, Kelly-Ann, Cicuttini, Flavia, Hinman, Rana S., Hodges, Paul W., van den Hoorn, Wolbert, Wang, Yuanyuan, Wrigley, Tim V.   +7 more
core   +1 more source

The effect of the aluminum chloride – quercetin complex on Ca(2+),Mg(2+)-ATPase activity and contraction dynamic properties of muscle tibialis anterior from Rana temporaria [PDF]

The Ukrainian Biochemical Journal, 2015
Combined effect of aluminum chloride and quercetin solutions on the enzymatic activity and contraction dynamics of muscle fiber bundles of the Rana temporaria m. tibialis anterior was investigated.
D. M. Nozdrenko, O. M. Аbramchuk, V. M. Soroca, N. S. Miroshnichenko   +3 more
doaj   +1 more source

Muscle contraction: A mechanical perspective [PDF]

The European Physical Journal E, 2010
In this paper we present a purely mechanical analog of the conventional chemo-mechanical modeling of muscle contraction. We abandon the description of kinetics of the power stroke in terms of jump processes and instead resolve the continuous stochastic evolution on an appropriate energy landscape.
Marcucci L., Truskinovsky L.
openaire   +6 more sources

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Structural Biochemistry of Muscle Contraction

Annual Review of Biochemistry, 2023
Muscles are essential for movement and heart function. Contraction and relaxation of muscles rely on the sliding of two types of filaments—the thin filament and the thick myosin filament. The thin filament is composed mainly of filamentous actin (F-actin), tropomyosin, and troponin.
Wang, Zhexin, Raunser, Stefan
openaire   +2 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Upper Limbs Muscle Co-contraction Changes Correlated With the Impairment of the Corticospinal Tract in Stroke Survivors: Preliminary Evidence From Electromyography and Motor-Evoked Potential

Frontiers in Neuroscience, 2022
ObjectiveIncreased muscle co-contraction of the agonist and antagonist muscles during voluntary movement is commonly observed in the upper limbs of stroke survivors. Much remain to be understood about the underlying mechanism.
Wenfei Sheng, Shijue Li, Jiangli Zhao, Yujia Wang, Zichong Luo, Wai Leung Ambrose Lo, Minghui Ding, Chuhuai Wang, Le Li   +8 more
doaj   +1 more source

Elastic, Viscous, and Mass Load Effects on Poststroke Muscle Recruitment and Co-contraction During Reaching: A Pilot Study [PDF]

, 2009
Background: Resistive exercise after stroke can improve strength (force-generating capacity) without increasing spasticity (velocity-dependent hypertonicity). However, the effect of resistive load type on muscle activation and co-contraction after stroke
Stoeckmann, Tina M., Sullivan, Katherine J., Scheidt, Robert A.   +2 more
core   +1 more source

Effects of different vibration frequencies, amplitudes and contraction levels on lower limb muscles during graded isometric contractions superimposed on whole body vibration stimulation [PDF]

, 2018
Background: Indirect vibration stimulation, i.e., whole body vibration or upper limb vibration, has been investigated increasingly as an exercise intervention for rehabilitation applications.
Bovenzi M, Cochrane DJ, Cormie P, Krause A, Nordlund MM, Pujari AN   +5 more
core   +2 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source