Results 51 to 60 of about 1,945,583 (386)

Multiscale Modeling of Skeletal Muscle Active Contraction in Relation to Mechanochemical Coupling of Molecular Motors

open access: yesMicromachines, 2015
In this work, a mathematical model was developed to relate the mechanochemical characterizations of molecular motors with the macroscopic manifestation of muscle contraction.
Jiangcheng Chen   +4 more
doaj   +1 more source

Critical role of actin-associated proteins in smooth muscle contraction, cell proliferation, airway hyperresponsiveness and airway remodeling

open access: yesRespiratory Research, 2015
Asthma is characterized by airway hyperresponsiveness and airway remodeling, which are largely attributed to increased airway smooth muscle contractility and cell proliferation.
D. Tang
semanticscholar   +1 more source

Poorly Understood Aspects of Striated Muscle Contraction

open access: yesBioMed Research International, 2015
Muscle contraction results from cyclic interactions between the contractile proteins myosin and actin, driven by the turnover of adenosine triphosphate (ATP).
A. Månsson, D. Rassier, G. Tsiavaliaris
semanticscholar   +1 more source

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

open access: yesDiabetes, 2016
Earlier studies have demonstrated that muscle insulin sensitivity to stimulate glucose uptake is enhanced several hours after an acute bout of exercise. Using AICAR, we recently demonstrated that prior activation of AMPK is sufficient to increase insulin
R. Kjøbsted   +8 more
semanticscholar   +1 more source

Muscle contraction: A mechanical perspective [PDF]

open access: yesThe European Physical Journal E, 2010
In this paper we present a purely mechanical analog of the conventional chemo-mechanical modeling of muscle contraction. We abandon the description of kinetics of the power stroke in terms of jump processes and instead resolve the continuous stochastic evolution on an appropriate energy landscape.
Marcucci L., Truskinovsky L.
openaire   +6 more sources

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

In vivo myograph measurement of muscle contraction at optimal length

open access: yesBioMedical Engineering OnLine, 2007
Background Current devices for measuring muscle contraction in vivo have limited accuracy in establishing and re-establishing the optimum muscle length.
Ahmed Aminul   +6 more
doaj   +1 more source

Bio-Inspired Design of Artificial Striated Muscles Composed of Sarcomere-Like Contraction Units (preprint) [PDF]

open access: yesarXiv, 2021
Biological muscles have always attracted robotics researchers due to their efficient capabilities in compliance, force generation, and mechanical work. Many groups are working on the development of artificial muscles, however, state-of-the-art methods still fall short in performance when compared with their biological counterpart.
arxiv  

Structural Biochemistry of Muscle Contraction

open access: yesAnnual Review of Biochemistry, 2023
Muscles are essential for movement and heart function. Contraction and relaxation of muscles rely on the sliding of two types of filaments—the thin filament and the thick myosin filament. The thin filament is composed mainly of filamentous actin (F-actin), tropomyosin, and troponin.
Wang, Zhexin, Raunser, Stefan
openaire   +2 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy