Results 51 to 60 of about 489,683 (360)
Background Current devices for measuring muscle contraction in vivo have limited accuracy in establishing and re-establishing the optimum muscle length.
Ahmed Aminul+6 more
doaj +1 more source
ObjectiveIncreased muscle co-contraction of the agonist and antagonist muscles during voluntary movement is commonly observed in the upper limbs of stroke survivors. Much remain to be understood about the underlying mechanism.
Wenfei Sheng+8 more
doaj +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
This study assessed changes in electrical impedance myography (EIM) at different levels of isometric muscle contraction as well as during exhaustive exercise at 60% maximum voluntary contraction (MVC) until task failure.
Le Li+4 more
doaj +1 more source
Regional Differences in Biceps Femoris Long Head Stiffness during Isometric Knee Flexion
This study sought to investigate whether the stiffness of the biceps femoris long head differs between proximal and distal regions during isometric knee flexion at different contraction intensities and muscle lengths. Twelve healthy individuals performed
João R. Vaz+4 more
doaj +1 more source
Ablation of smooth muscle myosin heavy chain SM2 increases smooth muscle contractility and results in postnatal death in mice [PDF]
The smooth muscle myosin heavy chains (SMHC) are motor proteins powering smooth muscle contraction. Alternate splicing of SHMC gene at the C-terminus produces SM1, and SM2 myosin isoforms; SM2 (200 kDa) contains a unique 9-amino-acid sequence at the ...
Aikawa+22 more
core +3 more sources
Muscle contraction: A mechanical perspective [PDF]
In this paper we present a purely mechanical analog of the conventional chemo-mechanical modeling of muscle contraction. We abandon the description of kinetics of the power stroke in terms of jump processes and instead resolve the continuous stochastic evolution on an appropriate energy landscape.
Marcucci L., Truskinovsky L.
openaire +5 more sources
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Elastic, Viscous, and Mass Load Effects on Poststroke Muscle Recruitment and Co-contraction During Reaching: A Pilot Study [PDF]
Background: Resistive exercise after stroke can improve strength (force-generating capacity) without increasing spasticity (velocity-dependent hypertonicity). However, the effect of resistive load type on muscle activation and co-contraction after stroke
Stoeckmann, Tina M.+2 more
core +1 more source
Effects of cervical muscle fatigue on the perception of the subjective vertical and horizontal [PDF]
Introduction: Cervical functional capacity outcome measures that are simple and reliable are urgently needed in order permit accurate assessment/reassessment during treatments and rehabilitation.
Fagan, Michael J+2 more
core +2 more sources