Results 61 to 70 of about 1,945,583 (386)

Regulation of gastric smooth muscle contraction via Ca2+-dependent and Ca2+-independent actin polymerization.

PLoS ONE, 2018
In gastrointestinal smooth muscle, acetylcholine induced muscle contraction is biphasic, initial peak followed by sustained contraction. Contraction is regulated by phosphorylation of 20 kDa myosin light chain (MLC) at Ser19, interaction of actin and ...
Sunila Mahavadi, Ancy D Nalli, Hongxia Wang, Derek M Kendig, Molly S Crowe, Vijay Lyall, John R Grider, Karnam S Murthy   +7 more
doaj   +1 more source

Localized Electrical Impedance Myography of the Biceps Brachii Muscle during Different Levels of Isometric Contraction and Fatigue

Sensors, 2016
This study assessed changes in electrical impedance myography (EIM) at different levels of isometric muscle contraction as well as during exhaustive exercise at 60% maximum voluntary contraction (MVC) until task failure.
Le Li, Henry Shin, Xiaoyan Li, Sheng Li, Ping Zhou   +4 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

After-Fatigue Condition: A Novel Analysis Based on Surface EMG Signals [PDF]

arXiv, 2023
This study introduces a novel muscle activation analysis based on surface electromyography (sEMG) signals to assess the muscle's after-fatigue condition. Previous studies have mainly focused on the before-fatigue and fatigue conditions. However, a comprehensive analysis of the after-fatigue condition has been overlooked.
arxiv  

The role of titin in eccentric muscle contraction

Journal of Experimental Biology, 2014
Muscle contraction and force regulation in skeletal muscle have been thought to occur exclusively through the relative sliding of and the interaction between the contractile filaments actin and myosin.
W. Herzog
semanticscholar   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Model-based control of skeletal muscle using muscle-contraction models

Journal of Biomechanical Science and Engineering
Bioactuators using skeletal muscle are expected to be applied to medical and welfare equipment as functional materials with self-growth functions. In this regard, their contraction force must be controlled with high accuracy for the desired operation ...
Mutsuki HAGIWARA, Takumi MOCHIDA, Wataru HIJIKATA   +2 more
doaj   +1 more source

Cytoprotective Role of Nrf2 in Electrical Pulse Stimulated C2C12 Myotube.

PLoS ONE, 2015
Regular physical exercise is central to a healthy lifestyle. However, exercise-related muscle contraction can induce reactive oxygen species and reactive nitrogen species (ROS/RNS) production in skeletal muscle.
Masaki Horie, Eiji Warabi, Shoichi Komine, Sechang Oh, Junichi Shoda   +4 more
doaj   +1 more source

Mitochondrial Ca2+ uptake in skeletal muscle health and disease [PDF]

, 2016
Muscle uses Ca2+ as a messenger to control contraction and relies on ATP to maintain the intracellular Ca2+ homeostasis. Mitochondria are the major sub-cellular organelle of ATP production. With a negative inner membrane potential, mitochondria take up Ca2+ from their surroundings, a process called mitochondrial Ca2+ uptake.
arxiv   +1 more source

I am Robot: Neuromuscular Reinforcement Learning to Actuate Human Limbs through Functional Electrical Stimulation [PDF]

arXiv, 2021
Human movement disorders or paralysis lead to the loss of control of muscle activation and thus motor control. Functional Electrical Stimulation (FES) is an established and safe technique for contracting muscles by stimulating the skin above a muscle to induce its contraction.
arxiv