Results 61 to 70 of about 490,179 (385)

Regulation of gastric smooth muscle contraction via Ca2+-dependent and Ca2+-independent actin polymerization.

PLoS ONE, 2018
In gastrointestinal smooth muscle, acetylcholine induced muscle contraction is biphasic, initial peak followed by sustained contraction. Contraction is regulated by phosphorylation of 20 kDa myosin light chain (MLC) at Ser19, interaction of actin and ...
Sunila Mahavadi, Ancy D Nalli, Hongxia Wang, Derek M Kendig, Molly S Crowe, Vijay Lyall, John R Grider, Karnam S Murthy   +7 more
doaj   +1 more source

In vivo myograph measurement of muscle contraction at optimal length

BioMedical Engineering OnLine, 2007
Background Current devices for measuring muscle contraction in vivo have limited accuracy in establishing and re-establishing the optimum muscle length.
Ahmed Aminul, Pawlak Matthias, Karst Matthias, Weilbach Christian, Rahe-Meyer Niels, Piepenbrock Siegfried, Winterhalter Michael   +6 more
doaj   +1 more source

Bio-Inspired Design of Artificial Striated Muscles Composed of Sarcomere-Like Contraction Units (preprint) [PDF]

arXiv, 2021
Biological muscles have always attracted robotics researchers due to their efficient capabilities in compliance, force generation, and mechanical work. Many groups are working on the development of artificial muscles, however, state-of-the-art methods still fall short in performance when compared with their biological counterpart.
arxiv  

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Localized Electrical Impedance Myography of the Biceps Brachii Muscle during Different Levels of Isometric Contraction and Fatigue

Sensors, 2016
This study assessed changes in electrical impedance myography (EIM) at different levels of isometric muscle contraction as well as during exhaustive exercise at 60% maximum voluntary contraction (MVC) until task failure.
Le Li, Henry Shin, Xiaoyan Li, Sheng Li, Ping Zhou   +4 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Model-based control of skeletal muscle using muscle-contraction models

Journal of Biomechanical Science and Engineering
Bioactuators using skeletal muscle are expected to be applied to medical and welfare equipment as functional materials with self-growth functions. In this regard, their contraction force must be controlled with high accuracy for the desired operation ...
Mutsuki HAGIWARA, Takumi MOCHIDA, Wataru HIJIKATA   +2 more
doaj   +1 more source

Cytoprotective Role of Nrf2 in Electrical Pulse Stimulated C2C12 Myotube.

PLoS ONE, 2015
Regular physical exercise is central to a healthy lifestyle. However, exercise-related muscle contraction can induce reactive oxygen species and reactive nitrogen species (ROS/RNS) production in skeletal muscle.
Masaki Horie, Eiji Warabi, Shoichi Komine, Sechang Oh, Junichi Shoda   +4 more
doaj   +1 more source

After-Fatigue Condition: A Novel Analysis Based on Surface EMG Signals [PDF]

arXiv, 2023
This study introduces a novel muscle activation analysis based on surface electromyography (sEMG) signals to assess the muscle's after-fatigue condition. Previous studies have mainly focused on the before-fatigue and fatigue conditions. However, a comprehensive analysis of the after-fatigue condition has been overlooked.
arxiv  

Effects of cervical muscle fatigue on the perception of the subjective vertical and horizontal [PDF]

, 2014
Introduction: Cervical functional capacity outcome measures that are simple and reliable are urgently needed in order permit accurate assessment/reassessment during treatments and rehabilitation.
Fagan, Michael J, Fagan, Michael J., Gosselin, Guy   +2 more
core   +2 more sources