Results 71 to 80 of about 490,179 (385)

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Estimation of quadriceps femoris muscle dysfunction in the early period after surgery of the knee joint using shear-wave elastography

BMJ Open Sport & Exercise Medicine, 2018
Objectives Orthopaedic surgery of the knee joint results in functional deterioration of the quadriceps femoris muscle. However, little is known about quadriceps femoris muscle dysfunction in the early postsurgical period.
Makoto Kawai, Keigo Taniguchi, Tomoyuki Suzuki, Masaki Katayose   +3 more
doaj   +1 more source

Regional Differences in Biceps Femoris Long Head Stiffness during Isometric Knee Flexion

Journal of Functional Morphology and Kinesiology, 2021
This study sought to investigate whether the stiffness of the biceps femoris long head differs between proximal and distal regions during isometric knee flexion at different contraction intensities and muscle lengths. Twelve healthy individuals performed
João R. Vaz, Tiago Neto, José Pedro Correia, Jorge Infante, Sandro R. Freitas   +4 more
doaj   +1 more source

Mitochondrial Ca2+ uptake in skeletal muscle health and disease [PDF]

, 2016
Muscle uses Ca2+ as a messenger to control contraction and relies on ATP to maintain the intracellular Ca2+ homeostasis. Mitochondria are the major sub-cellular organelle of ATP production. With a negative inner membrane potential, mitochondria take up Ca2+ from their surroundings, a process called mitochondrial Ca2+ uptake.
arxiv   +1 more source

I am Robot: Neuromuscular Reinforcement Learning to Actuate Human Limbs through Functional Electrical Stimulation [PDF]

arXiv, 2021
Human movement disorders or paralysis lead to the loss of control of muscle activation and thus motor control. Functional Electrical Stimulation (FES) is an established and safe technique for contracting muscles by stimulating the skin above a muscle to induce its contraction.
arxiv  

The Motor Innervation of a Triply Innervated Crustacean Muscle [PDF]

, 1939
The crustacean muscle is extremely sensitive to mechanical injury. This is due to the fact that the muscle fibres are innervated by a feltwork of nerve fibres which surrounds them.
van Harreveld, A.
core  

Ablation of smooth muscle myosin heavy chain SM2 increases smooth muscle contractility and results in postnatal death in mice [PDF]

, 2008
The smooth muscle myosin heavy chains (SMHC) are motor proteins powering smooth muscle contraction. Alternate splicing of SHMC gene at the C-terminus produces SM1, and SM2 myosin isoforms; SM2 (200 kDa) contains a unique 9-amino-acid sequence at the ...
Aikawa, Babij, Babu, Cher, Craig, G. J. Babu, Kelley, Lauzon, Loukianov, M. Chi, M. Periasamy, Miano, Morano, Murphy, Nagai, Nagai, Rovner, Rovner, S. Vedamoorthyrao, SOMLYO, Wang, Y. Zhou, Zhou   +22 more
core   +3 more sources

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source

Experimental research models for skeletal muscle contraction

Journal of Physical Fitness and Sports Medicine, 2016
Skeletal muscle has an important role besides its obvious function in physical movement and locomotion; namely, it maintains whole-body metabolism. Maintaining muscle mass and quality with regular exercise is closely related to quality of life and a ...
Yasuko Manabe, Nobuharu L. Fujii
doaj   +1 more source

Activation of a muscle as a mapping of stress-strain curves [PDF]

Extreme Mechanics Letters 28 (2019): 37-42, 2019
The mathematical modeling of the contraction of a muscle is a crucial problem in biomechanics. Several different models of muscle activation exist in literature. A possible approach to contractility is the so-called active strain: it is based on a multiplicative decomposition of the deformation gradient into an active contribution, accounting for the ...
arxiv   +1 more source