Results 261 to 270 of about 779,091 (316)

BMP signaling controls muscle mass

Nature Genetics, 2013
Cell size is determined by the balance between protein synthesis and degradation. This equilibrium is affected by hormones, nutrients, energy levels, mechanical stress and cytokines. Mutations that inactivate myostatin lead to excessive muscle growth in animals and humans, but the signals and pathways responsible for this hypertrophy remain largely ...
Sartori R, Schirwis E, BLAAUW, BERT, Bortolanza S, Zhao J, ENZO, ELENA, Stantzou A, Mouisel E, TONIOLO, LUANA, Ferry A, Stricker S, Goldberg AL, DUPONT, SIRIO, PICCOLO, STEFANO, Amthor H, SANDRI, MARCO   +15 more
openaire   +3 more sources

Muscle Mass Versus Muscle Strength and Performance: Is Muscle Mass Measurement Alone Enough?

2019
In the world of advanced liver disease, no person can deny the loss of physical function that occurs to patients with cirrhosis. As the disease progresses, the physical manifestations of muscle mass loss and reduced physical function are apparent. Providers, patients, and caregivers to patients know this all too well.
Matthew R. Kappus, Pranab Barman
openaire   +1 more source

Molecular mechanisms modulating muscle mass

Trends in Molecular Medicine, 2003
Skeletal muscle atrophy occurs in multiple clinical settings, including cancer, AIDS and sepsis, and is caused in part by an increase in the rate of ATP-dependent ubiquitin-mediated proteolysis. The expression of two recently identified genes encoding ubiquitin-protein ligases, MAFbx/Atrogin-1 and MuRF1, has been shown to increase during muscle atrophy.
openaire   +2 more sources

Impact of Preoperative Muscle Mass Maintenance and Perioperative Muscle Mass Loss Prevention After Pancreatectomy

Pancreas, 2022
Objectives We investigated how preoperative sarcopenia and perioperative muscle mass changes affect postoperative nutritional parameters in patients undergoing pancreatectomy. Methods This study included 164 patients undergoing pancreatectomy between January 2011 and October 2018 ...
Takeru Maekawa, Hiromitsu Maehira, Hiroya Iida, Haruki Mori, Nobuhito Nitta, Aya Tokuda, Sachiko Kaida, Toru Miyake, Katsushi Takebayashi, Masaji Tani   +9 more
openaire   +2 more sources

Signaling pathways perturbing muscle mass

Current Opinion in Clinical Nutrition and Metabolic Care, 2010
To discuss the mechanisms of muscle loss during cachexia.Cachexia can be defined as a wasting of lean body mass that cannot be reversed nutrionally, indicating a dysregulation in the pathways maintaining body composition. In skeletal muscle, during cachexia, there is an upregulation of protein degradation. A search for transcriptional markers of muscle
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Nutritional Supplements to Increase Muscle Mass

Critical Reviews in Food Science and Nutrition, 1999
Although nutritional supplements purported to increase muscle mass are widely available at health food stores, gyms, by mail order, and over the Internet, many of these supplements have little or no data to support their claims. This article reviews the theory and research behind popular nutritional supplements commonly marketed as muscle mass builders.
Clarkson, PM, Rawson, ES
openaire   +2 more sources